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CYP24A1

Basics

Aliases:
This biomarker is also known as:
  • CYP24,
  • exo-mitochondrial protein,
  • cytochrome P450, family 24, subfamily A, polypeptide 1,
  • HCAI,
  • 1,25-@dihydroxyvitamin D3 24-hydroxylase,
  • EC 1.14.13.126,
  • 24-OHase,
  • CP24,
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase),
  • vitamin D 24-hydroxylase,
  • P450-CC24,
  • Vitamin D(3) 24-hydroxylase,
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial,
  • Cytochrome P450-CC24,
  • Cytochrome P450 24A1,

Description…

The CYP24A1 protein is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP24A1 is involved in maintaining calcium homeostasis and catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). Several different isoforms exist, encoded by alternatively spliced transcript variants.

Attributes

QA State: Under Review
Type: Gene
Short Name:
HGNC Name: CYP24A1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.