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CYP24A1

Basics

Aliases:
This biomarker is also known as:
  • cytochrome P450, family 24, subfamily A, polypeptide 1,
  • Cytochrome P450 24A1,
  • P450-CC24,
  • EC 1.14.13.126,
  • 1,25-@dihydroxyvitamin D3 24-hydroxylase,
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial,
  • CP24,
  • CYP24,
  • vitamin D 24-hydroxylase,
  • 24-OHase,
  • exo-mitochondrial protein,
  • HCAI,
  • Vitamin D(3) 24-hydroxylase,
  • Cytochrome P450-CC24,
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase),

View in BioMuta

Description…

The CYP24A1 protein is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP24A1 is involved in maintaining calcium homeostasis and catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). Several different isoforms exist, encoded by alternatively spliced transcript variants.

Attributes

QA State: Under Review
Type: Gene
Short Name:
HGNC Name: CYP24A1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement