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CD1A

Basics

Aliases:
This biomarker is also known as:
  • T6,
  • R4,
  • T-cell surface antigen T6/Leu-6,
  • hTa1 thymocyte antigen,
  • cluster of differentiation 1 A,
  • FCB6,
  • CD1A antigen, a polypeptide,
  • HTA1,
  • CD1,
  • CD1a molecule,
  • cortical thymocyte antigen CD1A,
  • T-cell surface glycoprotein CD1a,
  • epidermal dendritic cell marker CD1a,
  • differentiation antigen CD1-alpha-3,
  • CD1a antigen,

Description…

CD1A is a transmembrane glycoprotein that is structurally related to the major histocompatibility complex (MHC) proteins and forms heterodimers with beta-2-microglobulin. CD1A functions as an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: CD1A

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

CD1A was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Biomuta

Mutation Statistics

Gene Name: CD1A
UniProt Accession #: P06126
Mutated Sites Count: 107
Associated Pubmed ID Count 17
CancerDO Count 24
Affected Protein Function Sites Count: 5

View in BioMuta