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This biomarker is also known as:
  • Calcitonin-Related Polypeptide Alpha,
  • Calcitonin Gene-Related Peptide I,
  • Katacalcin,
  • CGRP-1,
  • CGRP,
  • CALC1,
  • KC,
  • Calcitonin 1,
  • Alpha-Type CGRP,
  • Calcitonin,
  • CT,
  • CGRP1,
  • Calcitonin/Calcitonin-Related Polypeptide, Alpha,


From NCBI Gene: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]


QA State: Curated
Type: Gene
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…

Head & neck, NOS


Phase: One
QA State: Curated


No additional data available.

Performance Comment

CALCA is one of eight genes on a panel of differentially methylated genes from normal and OSCC clinical samples from patients with heterogenous risk profiles chosen for further validation. The eight genes are: HOXA9, NID2, GATA4, KIF1A, EDNRB, MCAM, DCC, and CALCA.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


Mutation Statistics

Gene Name: CALCA
UniProt Accession #: P01258
Mutated Sites Count: 23
Associated Pubmed ID Count 7
CancerDO Count 14
Affected Protein Function Sites Count: 2

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