Personal tools

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit

Updates regarding government operating status and resumption of normal operations can be found at

You are here: Home / Biomarkers / AP3B2



This biomarker is also known as:
  • beta-3B-adaptin,
  • AP-3 complex subunit beta-2,
  • Adapter-related protein complex 3 subunit beta-2,
  • adaptor protein complex AP-3 subunit beta-2,
  • adapter-related protein complex 3 subunit beta-2,
  • NAPTB,
  • Clathrin assembly protein complex 3 beta-2 large chain,
  • neuron-specific vesicle coat protein beta-NAP,
  • Neuron-specific vesicle coat protein beta-NAP,
  • Beta-3B-adaptin,
  • Neuronal adaptin-like protein, beta-subunit,
  • adaptor-related protein complex 3, beta 2 subunit,
  • clathrin assembly protein complex 3 beta-2 large chain,
  • Adaptor protein complex AP-3 subunit beta-2,


AP3B2 is the beta 2 subunit of adaptor-related protein complex 3, a neuron-specific complex that is thought to serve neuron-specific functions such as neurotransmitter release.


QA State: Curated
Type: Protein
Short Name:
HGNC Name: AP3B2


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

AP3B2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


Mutation Statistics

Gene Name: AP3B2
UniProt Accession #: Q13367
Mutated Sites Count: 127
Associated Pubmed ID Count 8
CancerDO Count 20
Affected Protein Function Sites Count: 1

View in BioMuta