Aliases:This biomarker is also known as:
- RNase 5,
- Ribonuclease 5,
- EC 3.1.27,
- epididymis luminal protein 168,
Angiogenin, or ANG, is a mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. ANG binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues.
|QA State:||Under Review|
There are no datasets associated with this biomarker.