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ADH5

Basics

Aliases:
This biomarker is also known as:
  • EC 1.1.1.1,EC 1.1.1.-,EC 1.1.1.284,
  • GSNOR,
  • alcohol dehydrogenase (class III), chi polypeptide,
  • S-(hydroxymethyl)glutathione dehydrogenase,
  • Alcohol dehydrogenase class chi chain,
  • Glutathione-dependent formaldehyde dehydrogenase,
  • Alcohol dehydrogenase class-III,
  • GSH-FDH,
  • FDH,
  • FALDH,
  • alcohol dehydrogenase 5 (class III), chi polypeptide,
  • alcohol dehydrogenase class-III,
  • alcohol dehydrogenase class chi chain,
  • formaldehyde dehydrogenase,
  • ADHX,
  • glutathione-dependent formaldehyde dehydrogenase,
  • ADH-3,
  • Alcohol dehydrogenase 5,
  • alcohol dehydrogenase class-3,

View in BioMuta

Description…

ADH5 is a member of the alcohol dehydrogenase family. This protein forms a homodimer. ADH5 is ineffective in oxidizing ethanol, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. There are several non-transcribed pseuodogenes related to this gene.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: ADH5

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ADH5 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement