12th EDRN Scientific Workshop - Wednesday 24 March Agenda

20th Year of EDRN: Making Cancer Detection Possible

Wednesday, March 24, 2021 (10:00 a.m. - 5:45 p.m. Eastern Daylight Time)

10:00 a.m. - 10:05 a.m. EDT
(all times Eastern Daylight Time)

Welcome

  • Joshua LaBaer, MD, PhD, Arizona State University/The Biodesign Institute
  • Arul Chinnaiyan, MD, PhD, University of Michigan
  • Sudhir Srivastava, PhD, MPH, National Cancer Institute
10:05 a.m. - 10:25 a.m. EDT

17: Cancer Biomarkers and Disparity in Underserved Populations

  • Olufunmilayo Olopade, MD, FACP, University of Chicago Medicine
10:25 a.m. - 10:30 a.m. EDT

Q&A

10:30 a.m. - 1:15 p.m. EDT

Session 4 - Academic-Industry Partnership Forum

10:30 a.m. - 10:35 p.m. EDT

Introduction to the Session

Moderator:
  • Ernest Hawk, MD, MPH, The University of Texas MD Anderson Cancer Center
10:35 a.m. - 10:50 a.m. EDT

18: A Revolution in Early Cancer Detection

  • Josh Ofman, MD, MSHS, GRAIL, Inc.
10:50 a.m. - 11:05 a.m. EDT

19: Systems-level thinking facilitating the introduction of Multi-Cancer Early Detection (MCED) tests

  • Peter Keeling, Diaceutics
11:05 a.m. - 11:20 a.m. EDT

20: Multi-Cancer Early Detection: The Challenges to Be Overcome to Reach the Goal of MCDE

  • Kathryn Lang, MD, Guardant Health
11:20 a.m. - 11:35 a.m. EDT

Break

11:35 a.m. - 11:50 a.m. EDT

21: Multi-cancer screening guides patient management in a study enabled by academia-health system- industry partnership

  • Isaac Kinde, MD, PhD, Thrive Detect
11:50 a.m. - 12:05 p.m. EDT

22: TBD

  • Graham Lidgard, PhD, Exact Sciences
12:05 p.m. - 1:15 p.m. EDT

Panel Discussion

  • Eric Fung, MD, PhD, GRAIL, Inc.
  • Daniel Chan PhD, Johns Hopkins University
  • Johan Skog, PhD, Exosome Diagnostics
  • Reena Philip, PhD, Food and Drug Administration
  • Nickolas Papadopoulos, PhD, Johns Hopkins University
1:15 p.m. - 1:30 p.m. EDT

Break

1:30 p.m. - 3:30 p.m. EDT

Session 5 - Public Health Consideration of Biomarker Research

 

Speakers will summarize the highlights of the topics that were discussed by the EDRN Steering Committee in October 2020

Moderators:
  • Philip Castle, PhD, MPH, National Cancer Institute tentative
  • Ruth Etzioni, PhD, Fred Hutchinson Cancer Research Center
1:30 p.m. - 1:50 p.m. EDT

23: What Target Sensitivity and Specificity Might Confer Clinical Utility?

  • Steve Skates, PhD, Massachusetts General Hospital/Harvard
  • Robert Schoen, MD, University of Pittsburgh Cancer Institute
1:50 p.m. - 2:00 p.m. EDT

Q&A

2:00 p.m. - 2:20 p.m. EDT

24: MAPBD – Model-based Augmentation of the Phases of Biomarker Development for a New Era of Early Detection

  • Ruth Etzioni, PhD, Fred Hutchinson Cancer Research Center
2:20 p.m. - 2:30 p.m. EDT

Q&A

2:30 p.m. - 3:05 p.m. EDT

25: Health Disparity and Biomarker Research

  • Christopher Li, MD, PhD, Fred Hutchinson Cancer Research Center
  • Timothy P. Quinn, MD, Emory University School of Medicine
  • Pierre Massion, MD, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center
  • Guest Speaker: Melissa Davis, PhD, Weill Cornell College of Medicine
3:05 p.m. - 3:15 p.m. EDT

Q&A

3:15 p.m. - 3:35 p.m. EDT

26: Study Designs for Clinical Utility Trials

  • Yingye Zheng, PhD, Fred Hutchinson Cancer Research Center
  • Steve Skates, PhD, Massachusetts General Hospital/Harvard
3:35 p.m. - 3:45 p.m. EDT

Q&A

3:45 p.m. - 4:00 p.m. EDT

Break

4:00 p.m. - 5:45 p.m. EDT

Session 6 - EDRN Early Stage Investigators Presentations

Moderators:

  • Karin Rodland, PhD, Pacific Northwest National Laboratory
  • Andrew Kossenkov, PhD, The Wistar Institute
4:00 p.m. - 4:12 p.m. EDT

27: Combinatorial Biomarker(s) for Pancreatic Cancer Diagnosis: Lessons from Transcriptome

  • Sukhwinder Kaur, PhD, University of Nebraska Medical Center
4:12 p.m. - 4:15 p.m. EDT

Q&A

4:15 p.m. - 4:27 p.m. EDT

28: Building a Radiogenomic Portrait of Pancreatic Intraductal Papillary Mucinous Neoplasm

  • Jennifer Permuth, PhD, MS, H. Lee Moffitt Cancer Center and Research Institute
4:27 p.m. - 4:30 p.m. EDT

Q&A

4:30 p.m. - 4:42p.m. EDT

29: Digital Microfluidic Methylation Assays for the Detection of Early-Stage Ovarian Cancer

  • Thomas Pisanic, PhD, Johns Hopkins University
4:42 p.m. - 4:45 p.m. EDT

Q&A

4:45 p.m. - 4:57 p.m. EDT

30: Urine Based Early Detection of High-Grade Prostate Cancer In A Racially Diverse
Patient Population

  • Indu Kohaar, PhD, Center for Prostate Disease Research
4:57 p.m. - 5:00 p.m. EDT

Q&A

5:00 p.m. - 5:12 p.m. EDT

31: MyProstateScore (MPS)

  • Jeff Tosoian, MD, MPH, University of Michigan
5:12 p.m. - 5:15 p.m. EDT

Q&A

5:15 p.m. - 5:27 p.m. EDT

32: Methylomic Biomarkers in GI Cancers: A Multi-phasic Case Study in Hepatocellular  Cancer

  • John Kisiel, MD, Mayo Clinic
5:27 p.m. - 5:30 p.m. EDT

Q&A

5:30 p.m. - 5:42 p.m. EDT

33: Advancing MS-Based Single-Cell Proteomics

  • Tao Liu, PhD, Pacific Northwest National Laboratory
5:42 p.m. - 5:45 p.m. EDT

Q&A

5:45 p.m. EDT

Adjourn for the Day

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