Tockman, Melvyn S.

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Biomarker Dev Lab At Moffitt Supplement Leading 0 0
The Biomarker Knowledge System Informatics Pilot Project Supplement To The Biomarker Development Laboratory at Moffitt (Bedlam) Coordinating 0 0
The Early Detection Research Network: Biomarker Reference Laboratories Involved 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
EDRN Resource Network Exchange Involved 0 0
Protocol for Comparing Promoter Hypermethylation Methods in NSCLC Coordinating 0 0
Standard Specimen Reference Set: Lung Involved 0 0


Publication NamePubMed IDJournal
A systematic review and lessons learned from early lung cancer detection trials using low-dose computed tomography of the chest. 12915809 Cancer Control
Advances in sputum analysis for screening and early detection of lung cancer. 10740657 Cancer Control
Consensus statements from the Second International Lung Cancer Molecular Biomarkers Workshop: a European strategy for developing lung cancer molecular diagnostics in high risk populations. 12118333 Int J Oncol
Considerations in developing successful, population-based molecular screening and prevention of lung cancer. 11147628 Cancer
Data mining techniques for cancer detection using serum proteomic profiling. 15364092 Artif Intell Med
Defective transforming growth factor beta signaling pathway in head and neck squamous cell carcinoma as evidenced by the lack of expression of activated Smad2. 11410498 Clin Cancer Res
Diagnosis of roentgenographically occult lung cancer by sputum cytology. 11901920 Clin Chest Med
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. 12114433 Clin Cancer Res
Discovery of distinct protein profiles specific for lung tumors and pre-malignant lung lesions by SELDI mass spectrometry. 12781425 Lung Cancer
Efficacy of two sputum collection techniques in patients with air flow obstruction. 10432886 Acta Cytol
Evaluating serial observations of precancerous lesions for further study as a trigger for early intervention. 12210622 Stat Med
Expression of early lung cancer detection marker: hnRNP-A2/B1 and its relation to microsatellite alteration in non-small cell lung cancer. 11714531 Lung Cancer
Expression of transforming growth factor beta type II receptors in head and neck squamous cell carcinoma. 10389906 Clin Cancer Res
Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk. 15901990 Eur J Cancer Prev
Loss of heterogeneous ribonucleoprotein A(2)/B(1) expression in thyroid neoplasms. 11421561 Endocr Pract
Lung cancer evolution to preinvasive management. 11901918 Clin Chest Med
Lung cancer: chemoprevention and intermediate effect markers. 11220665 IARC Sci Publ
Microsatellite instability at AAAG repeat sequences in respiratory tract cancers. 11146445 Int J Cancer
Moving to the routine management of pre symptomatic lung cancer. 11720735 Lung Cancer
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD. 15702235 Int J Mol Med
Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk. 11219768 Cancer Epidemiol Biomarkers Prev
Screening for lung cancer with CT: a preliminary cost-effectiveness analysis. 12006436 Chest
The early detection of occult lung cancer. 11091923 Chest Surg Clin N Am
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk. 15077011 Pharmacogenetics
Transforming growth factor beta receptors and p27kip in thyroid carcinoma. 9932593 Arch Otolaryngol Head Neck Surg
Transforming growth factor beta receptors in verrucous and squamous cell carcinoma. 10448730 Arch Otolaryngol Head Neck Surg
Transforming growth factor-beta type II receptors and smad proteins in follicular thyroid tumors. 10942134 Laryngoscope


Lung Cancer Early Detection
The goal of my Molecular Screening Program is to conduct translational research into the discovery of markers of neoplastic transformation and the use of these markers to screen for cancer risk and early detection in specimens from human populations.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Tockman, Melvyn S.
H. Lee Moffitt Cancer Center
M.D., Ph.D.
(813) 745-1720
Person ID
EDRN Title
EDRN Associate Member
To update contact information, please visit the Data Management and Coordinating Center .