Chia (Retired), David

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Breast tissue array Leading 0 0
The Early Detection Research Network: Biomarker Reference Laboratories Coordinating 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Early Detection of Urinary Bladder Cancer Involved 0 0
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma Involved 0 0
Lung Reference Set A Application: Lee Goodglick/ Eleftherios Diamandis- UCLA/MSH (2009) Leading 5 0
Soluble Mesothelin Related Peptide (SMRP) and Osteopontin (OPN) as Early Detection Markers for Malignant Mesothelioma (MM) Involved 4 0
Validation of Biomarkers for the Early Detection of Colorectal Adenocarcinoma (GLNE 010) Involved 4 0
Validation of Serum Markers for the Early Detection of Hepatocellular Carcinoma Involved 3 0


Publication NamePubMed IDJournal
A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma. 18316555 Clin Cancer Res
A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases. 21504557 J Transl Med
Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma. 19362088 Gastroenterology
Aromatase expression predicts survival in women with early-stage non small cell lung cancer. 17974992 Cancer Res
COX-2-dependent stabilization of survivin in non-small cell lung cancer. 14597555 FASEB J
Decreased expression of annexin A1 is correlated with breast cancer development and progression as determined by a tissue microarray analysis. 16949910 Hum Pathol
Differential expression of anterior gradient gene AGR2 in prostate cancer. 21144054 BMC Cancer
Direct electronic detection of prostate-specific antigen in serum. 17352433 Small
Elevated MED28 expression predicts poor outcome in women with breast cancer. 20584319 BMC Cancer
Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer. 21511357 Lung Cancer
Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival. 21689459 BMC Cancer
Expression of transcription factor Yin Yang 1 in prostate cancer. 15942652 Int J Oncol
Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence. 17947468 Clin Cancer Res
Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma. 23050525 N Engl J Med
Global levels of histone modifications predict prognosis in different cancers. 19349354 Am J Pathol
Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome. 19729831 Cancer Biomark
Higher levels of GATA3 predict better survival in women with breast cancer. 21078439 Hum Pathol
Loss of annexin A1 expression in human breast cancer detected by multiple high-throughput analyses. 15567174 Biochem Biophys Res Commun
Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. 22345575 Am J Physiol Lung Cell Mol Physiol
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. 20710044 Cancer Res
Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. 21600232 Steroids
Prostate cancer cell phenotypes based on AGR2 and CD10 expression. 23348903 Mod Pathol
Protein expression based multimarker analysis of breast cancer samples. 21651811 BMC Cancer
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. 19887480 Clin Cancer Res
Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group. 19072545 J Proteome Res


Genome expression assay
My interest has been in developing a simple assay to measure gene expression. DNA methylation has been suggested as a mechanism to control gene expression, by utilizing the property that methylated DNA can be inhibitory to PCR reaction.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Chia (Retired), David
University of California Los Angeles
(310) 206-3216
Person ID
EDRN Title
EDRN Associate Member
To update contact information, please visit the Data Management and Coordinating Center .