Brenner, Dean

Open Protocols

Protocol NameBiomarkersDatasets
Clinical and Analytical Validation of Cancer Biomarkers: Developmental Studies 0 0
Clinical Validation of Molecular Signatures of Cervical Neoplasia 0 0
Detection of cancer DNA markers in urine 0 0
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas Great Lakes New England (GLNE) Clinical Validation Center 6 0
Using the methylome to identify aggressive Barrett’s esophagus 0 0
Validation of Biomarkers for the Early Detection of Colorectal Adenocarcinoma (GLNE 010) 4 0

Closed Protocols

Protocol NameBiomarkersDatasets
EDRN Resource Network Exchange 0 0
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma 0 0
Preliminary Clinical Characterization of Serum Biomarkers for Colorectal Neoplasms 0 0
Preliminary Validation of Biomarkers for the Detection of Colorectal Adenomas (Team Project #1) 1 0
Standard Specimen Reference Set: Colon 0 0
Validation of Serum Markers for the Early Detection of Hepatocellular Carcinoma 3 0


Publication NamePubMed IDJournal
An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer. 15289361 Cancer Res
Biomarkers for cancer risk, early detection, and prognosis: the validation conundrum. 17932336 Cancer Epidemiol Biomarkers Prev
Breast cancer histology and receptor status characterization in Asian Indian and Pakistani women in the U.S.--a SEER analysis. 20459777 BMC Cancer
Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying. 19139000 Cancer Prev Res (Phila)
CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. 21169243 Clin Cancer Res
Design of early validation trials of biomarkers. 19305629 Cancer Inform
Detecting K-ras mutations in stool from fecal occult blood test cards in multiphasic screening for colorectal cancer. 17349741 Cancer Lett
Detection of a K-ras mutation in urine of patients with colorectal cancer. 17192038 Cancer Biomark
Detection of hypermethylated vimentin in urine of patients with colorectal cancer. 22251609 J Mol Diagn
Development of common data elements: the experience of and recommendations from the early detection research network. 12706181 Int J Med Inform
Development of common data elements: the experience of and recommendations from the early detection research network. 12706181 Int J Med Inform
Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. 15113102 J Proteome Res
Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis. 16117833 BMC Cancer
Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis. 16117833 BMC Cancer
Early detection of colon cancer: new tests on the horizon. 18422372 Mol Diagn Ther
Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice. 21937210 J Nutr Biochem
Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers. 22220206 PLoS One
Fecal DNA biomarkers for the detection of colorectal neoplasia: attractive, but is it feasible? 16077063 J Natl Cancer Inst
Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia. 14581353 Clin Cancer Res
Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer. 15096565 J Mol Diagn
Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer. 18089831 Cancer Res
Identification of a Specific Vimentin Isoform That Induces an Antibody Response in Pancreatic Cancer. 18769604 Biomark Insights
Interrogating DNA repair in cancer risk assessment. 16030087 Cancer Epidemiol Biomarkers Prev
Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. 22262812 Cancer Prev Res (Phila)
Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer). 19138994 Cancer Prev Res (Phila)
Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3. 14595809 Proteomics
Molecular targets and clinical cancer risk reductive interventions. 21075336 Prog Mol Biol Transl Sci
Multiplexed analysis of glycan variation on native proteins captured by antibody microarrays. 17417647 Nat Methods
Occurrence of autoantibodies to annexin I, 14-3-3 theta and LAMR1 in prediagnostic lung cancer sera. 18794547 J Clin Oncol
Pancreatic cancer serum detection using a lectin/glyco-antibody array method. 19072160 J Proteome Res
Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot. 18311904 J Proteome Res
Preferential isolation of fragmented DNA enhances the detection of circulating mutated k-ras DNA. 14709652 Clin Chem
Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: comparison to fecal occult stool blood test. 21896998 Cancer Biomark
Reliable gene expression measurements from fine needle aspirates of pancreatic tumors: effect of amplicon length and quality assessment. 20709792 J Mol Diagn
Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group. 19072545 J Proteome Res
To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.
Photograph of Brenner, Dean
University of Michigan
Person ID
EDRN Title
EDRN Associate Member
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