Open Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
Combining Avatar Mice and Targeted Mass Spectrometry to Identify Plasma Biomarkers of Breast Cancer	Involved	161	0
Ovarian cancer biomarker discovery by longitudinal change-point analyses in pre-diagnostic samples	Leading	0	0
Ovarian Cancer Detection by Uterine Lavage DNA and Serum Proteins: A Phase 2 Biomarker Study	Leading	26	0
Proteomic Genetic and Longitudinal Pathways to Ovarian Cancer Biomarkers	Coordinating	0	0
Validation of Early Detection Ovarian Cancer Biomarkers (Team Project)	Coordinating	149	0

Closed Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
Benign Breast Disease Team Project	Involved	25	1
DCIS Team Project	Involved	6	1

Publications

Publication Name	PubMed ID	Journal
A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer.	21372037	Cancer Prev Res (Phila)
Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass.	20471625	Am J Obstet Gynecol
Development of a multimarker assay for early detection of ovarian cancer.	20368574	J Clin Oncol
Differential diagnosis of a pelvic mass: improved algorithms and novel biomarkers.	22543921	Int J Gynecol Cancer
Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma.	35767427	Anal Chem
Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.	21372036	Cancer Prev Res (Phila)
Ovarian cancer screening: development of the risk of ovarian cancer algorithm (ROCA) and ROCA screening trials.	22543916	Int J Gynecol Cancer
Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders.	22284961	Am J Obstet Gynecol

Interests

Early detection of ovarian cancer

Discovery of blood biomarkers for early detection of ovarian cancer, design of algorithms from longitudinal biomarkers for early detection of ovarian cancer, design and conduct of screening trials for early detection of ovarian cancer.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Site

Massachusetts General Hospital

Degree(s)

Ph.D.

Email

sskates@mgh.harvard.edu

Fax

(617) 724-9878

Person ID

1076

Note

To update contact information, please visit the Data Management and Coordinating Center .