Li, Christopher

Open Protocols

Protocol NameBiomarkersDatasets
Benign Breast Disease Team Project 25 0
Biomarkers to Distinguish Aggressive Cancers from Non-aggressive or Non-progressing Cancer 0 0
EDRN Breast and Ovary Cancer CVC, Study 1: Preliminary validation of breast cancer early detection biomarker candidates from our WHI discovery project 0 0
EDRN Breast and Ovary Cancer CVC, Study 2: Phase 3 retrospective validation of ovarian cancer early detection markers in serial preclinical samples from the PLCO trial 0 0
EDRN Breast and Ovary Cancer CVC, Study 3: Phase 3 Validation of screening decision rules in preclinical UKCTOCS serial samples 0 0
EDRN Breast and Ovary Cancer CVC, Study 4: Phase 3 Validation of Ovarian Cancer Serum Markers in Preclinical WHI Samples 0 0
Identification of biomarkers for ER+ breast cancer 0 0
Study 5: Phase 2 and 3 Validations of Putative Breast Cancer Early Detection Candidates 0 0
Validation of Early Detection Ovarian Cancer Biomarkers (Team Project) 149 0

Closed Protocols

Protocol NameBiomarkersDatasets
Breast Reference Set Application: Chris Li-FHCRC (2013) 10 0
Breast Reference Set Application: Chris Li-FHCRC (2015) 10 0
DCIS Team Project 6 0
Triple Negative Breast Cancer Team Project 147 0

Publications

Publication NamePubMed IDJournal
Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study. 26319120 Breast Cancer Res Treat
Dermcidin expression is associated with disease progression and survival among breast cancer patients. 24562771 Breast Cancer Res Treat
Designing early detection programs for ovarian cancer. 22180403 Ann Oncol
Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study. 22903690 Breast Cancer Res Treat
Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study. 27745870 Surgery
Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility? 27001493 Clin Chem
Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125. 22155417 Gynecol Oncol
Identifying post-menopausal women at elevated risk for epithelial ovarian cancer. 26343159 Gynecol Oncol
Immunity to placental malaria. III. Impairment of interleukin(IL)-12, not IL-18, and interferon-inducible protein-10 responses in the placental intervillous blood of human immunodeficiency virus/malaria-coinfected women. 11756993 J Infect Dis
Impact of screening test performance and cost on mortality reduction and cost-effectiveness of multimodal ovarian cancer screening. 22750949 Cancer Prev Res (Phila)
Interpretation of single and serial measures of HE4 and CA125 in asymptomatic women at high risk for ovarian cancer. 22962406 Cancer Epidemiol Biomarkers Prev
JAK2 expression is associated with tumor-infiltrating lymphocytes and improved breast cancer outcomes: implications for evaluating JAK2 inhibitors. 24764577 Cancer Immunol Res
Longitudinal screening algorithm that incorporates change over time in CA125 levels identifies ovarian cancer earlier than a single-threshold rule. 23248253 J Clin Oncol
Potential role of HE4 in multimodal screening for epithelial ovarian cancer. 21917606 J Natl Cancer Inst
Protein and glycomic plasma markers for early detection of adenoma and colon cancer. 27821646 Gut
Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. 27769113 J Proteome Res
Recommendation to use exact P-values in biomarker discovery research in place of approximate P-values. 30099328 Cancer Epidemiol
To update protocols, publications, biomarkers, or science data, please contact the Informatics Center.
Photograph of Li, Christopher
Site
Fred Hutchinson Cancer Center
Degree(s)
M.D., Ph.D.
Email
cili@fredhutch.org
Person ID
1736
EDRN Title
EDRN Principal Investigator
Note
To update contact information, please visit the Data Management and Coordinating Center .