Killary, Ann M.

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Biomarkers for the Early Detection of Pancreatic Cancer Coordinating 0 0
Pancreatic Cancer Early Detection Stem Cell Biomarkers (CA117452 Set-Aside) Involved 0 1

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Pancreatic Reference Set Application- Ann Killary and Subrata Sen-MD Anderson (2012) Leading 3 0


Publication NamePubMed IDJournal
A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells. 6147198 Cell
A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity. 8390035 Oncogene
A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. 21071578 Cancer Prev Res (Phila)
A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality. 8646736 Cancer Genet Cytogenet
A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians. 21656579 Mol Carcinog
A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo. 8159756 Proc Natl Acad Sci U S A
An 80 Kb P1 clone from chromosome 3p21.3 suppresses tumor growth in vivo. 8957080 Oncogene
An isozyme-specific selective system for the recovery of mammalian cells deficient in hepatic alcohol dehydrogenase activity. 6383854 Exp Cell Res
Analysis of the functional role of chromosome 10 loss in human glioblastomas. 8104691 Cancer Res
Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13. 2947337 Somat Cell Mol Genet
Assignment of retinoblastoma susceptibility gene to mouse chromosome 14. 2781416 Somat Cell Mol Genet
Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians. 17505013 Clin Cancer Res
Characterization of 11 human sarcoma cell strains: evaluation of cytogenetics, tumorigenicity, metastasis, and production of angiogenic factors. 12237927 Cancer
Chromosomal assignment and trans regulation of the tyrosine aminotransferase structural gene in hepatoma hybrid cells. 2874483 Mol Cell Biol
Chromosomal assignments of genes for tissue plasminogen activator and urokinase in mouse. 2821634 Somat Cell Mol Genet
Chromosomal localization of the human annexin III (ANX3) gene. 1830024 Genomics
Chromosome 18 suppresses the tumorigenicity of prostate cancer cells. 11170278 Genes Chromosomes Cancer
Chromosome assignment of mouse insulin, colony stimulating factor 1, and low-density lipoprotein receptors. 3066742 Genomics
Concurrent cytogenetic, interphase fluorescence in situ hybridization and DNA flow cytometric analyses of a carcinoma ex-pleomorphic adenoma of parotid gland. 9844608 Cancer Genet Cytogenet
Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability. 1630913 Nucleic Acids Res
Cytogenetic analysis of a primary salivary gland myoepithelioma. 10459346 Cancer Genet Cytogenet
DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer. 19536326 PLoS Med
Definition of a tumor suppressor locus within human chromosome 3p21-p22. 1438292 Proc Natl Acad Sci U S A
Dinucleotide repeat polymorphism at the D3S196 locus. 2388857 Nucleic Acids Res
Dinucleotide repeat polymorphism at the D4S174 locus. 2388858 Nucleic Acids Res
Fine mapping of the NRC-1 tumor suppressor locus within chromosome 3p12. 17624313 Biochem Biophys Res Commun
Functional evidence for an ovarian cancer tumor suppressor gene on chromosome 22 by microcell-mediated chromosome transfer. 11175342 Oncogene
Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids. 8619133 Somat Cell Mol Genet
Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4. 2062841 Proc Natl Acad Sci U S A
Genetic manipulation by means of microcell-mediated transfer of normal human chromosomes into recipient mouse cells. 7001478 Proc Natl Acad Sci U S A
Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. 19910837 Pancreas
Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients. 20530239 Carcinogenesis
Genotypic characterization of a primary mucoepidermoid carcinoma of the parotid gland by cytogenetic, fluorescence in situ hybridization, and DNA ploidy analysis. 8689608 Cancer Genet Cytogenet
High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis. 11929809 Cancer Res
Isolation of microcell hybrid clones containing retroviral vector insertions into specific human chromosomes. 2823107 Mol Cell Biol
Isolation of thymidine kinase-deficient rat hepatoma cells by selection with bromodeoxyuridine, Hoechst 33258, and visible light. 6203516 Biochem Genet
Limited nonrandom chromosomal aberrations in a recurrent adenoid cystic carcinoma of the parotid gland. 9973962 Cancer Genet Cytogenet
Localization of metastasis suppressor gene(s) for rat prostatic cancer to the long arm of human chromosome 10. 8527392 Genes Chromosomes Cancer
Metastasis suppressor genes for prostate cancer. 8630227 Prostate Suppl
MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. 19723895 Cancer Prev Res (Phila)
Mouse melanoma growth stimulatory activity gene (Mgsa) is polymorphic and syntenic with the W, patch, rumpwhite, and recessive spotting loci on chromosome 5. 2575589 Genomics
MSX1 inhibits myoD expression in fibroblast x 10T1/2 cell hybrids. 7664340 Cell
Multiple unrelated translocations in a metastatic epimyoepithelial carcinoma of the parotid gland. 9428361 Cancer Genet Cytogenet
Physical and functional mapping of a tumor suppressor locus for renal cell carcinoma within chromosome 3p12. 9721855 Cancer Res
Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. 19020940 Ann Surg Oncol
Report of the sixth international workshop on human chromosome 3 mapping 1995. 8641130 Cytogenet Cell Genet
Sigje, a member of the small inducible gene family that includes platelet factor 4 and melanoma growth stimulatory activity, is on mouse chromosome 11. 2576529 Cytogenet Cell Genet
Structure and variability of human chromosome ends. 2300052 Mol Cell Biol
Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells. 9365833 Genes Chromosomes Cancer
Surgical decision-making affected by clinical and genetic screening of a novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. 9488521 Ann Surg
Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer. 21697764 Pancreas
Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality. 18345035 Oncogene
The genetic locus NRC-1 within chromosome 3p12 mediates tumor suppression in renal cell carcinoma independently of histological type, tumor microenvironment, and VHL mutation. 10232606 Cancer Res
Trisomy 5 as the sole chromosomal abnormality in a primary mucoepidermoid carcinoma of the minor salivary gland. 7923075 Cancer Genet Cytogenet
Tumor suppression and apoptosis of human prostate carcinoma mediated by a genetic locus within human chromosome 10pter-q11. 8637912 Proc Natl Acad Sci U S A
Unstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification. 3600632 Mol Cell Biol


functional genomics and biomarker discovery
Our laboratory has utilized a functional genomics approach for the physical mapping of novel tumor suppressor loci. Current research efforts involve the identification and characterization of the chromosome 3p pathway to tumorigenesis as a means of biomarker discovery in pancreatic cancer.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Killary, Ann M.
The University of Texas MD Anderson Cancer Center
Person ID
EDRN Title
EDRN Associate Member
To update contact information, please visit the Data Management and Coordinating Center .