Haab, Brian

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
A Biomarker Bakeoff in Early Stage Pancreatic Cancer Involved 11 0
Biomarkers for the Early Detection of Pancreatic Cancer Involved 0 0
Pancreatic Cancer Bake Off 2 Involved 4 0
Pancreatic Cyst Biomarker Validation Study Bake Off Involved 23 0
Pre-diagnostic Pancreatic Cancer Set Aside Project Involved 25 0
Validation of plasma biomarker panels for the early detection of pancreatic cancer Leading 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
Early Diagnosis of Pancreatic Cancer-Network Collaborative Studies Involved 0 0
Pancreatic Reference Set Application: Brian Haab-Van Andel (2012) Leading 2 0
Prostate Rapid Pre-Validation Set Involved 6 0
Prostate Rapid Reference Set Application: Brian Haab - Van Andel (2006) Leading 3 1


Publication NamePubMed IDJournal
A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas. 27992432 PLoS One
A Novel Mass Spectrometry Platform for Multiplexed N-Glycoprotein Biomarker Discovery from Patient Biofluids by Antibody Panel Based N-Glycan Imaging. 31177770 Anal Chem
Advances in Tools to Determine the Glycan-Binding Specificities of Lectins and Antibodies. 31848260 Mol Cell Proteomics
Automated Identification and Quantification of Signals in Multichannel Immunofluorescence Images: The SignalFinder-IF Platform. 31026417 Am J Pathol
Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. 24303806 J Proteome Res
Characterizing Protein Glycosylation through On-Chip Glycan Modification and Probing. 27809484 Anal Chem
Chemically-blocked antibody microarray for multiplexed high-throughput profiling of specific protein glycosylation in complex samples. 22588202 J Vis Exp
Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. 22439797 J Proteome Res
Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas. 21266527 Clin Cancer Res
Deciphering Protein Glycosylation by Computational Integration of On-chip Profiling, Glycan-array Data, and Mass Spectrometry. 30257876 Mol Cell Proteomics
Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens. 26431551 PLoS One
Determining lectin specificity from glycan array data using motif segregation and GlycoSearch software. 23839995 Curr Protoc Chem Biol
Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. 22623153 Proteomics
Global comparisons of lectin-glycan interactions using a database of analyzed glycan array data. 23399549 Mol Cell Proteomics
Glycan motif profiling reveals plasma sialyl-lewis x elevations in pancreatic cancers that are negative for sialyl-lewis A. 25733690 Mol Cell Proteomics
Glycans related to the CA19-9 antigen are elevated in distinct subsets of pancreatic cancers and improve diagnostic accuracy over CA19-9. 26998508 Cell Mol Gastroenterol Hepatol
High-throughput studies of protein glycoforms using antibody-lectin sandwich arrays. 21901603 Methods Mol Biol
Identification of blood-protein carriers of the CA 19-9 antigen and characterization of prevalence in pancreatic diseases. 21751362 Proteomics
Mining High-Complexity Motifs in Glycans: A New Language To Uncover the Fine Specificities of Lectins and Glycosidases. 29058413 Anal Chem
Modulation of glycan detection on specific glycoproteins by lectin multimerization. 23286506 Anal Chem
Prediction of glycan motifs using quantitative analysis of multi-lectin binding: Motifs on MUC1 produced by cultured pancreatic cancer cells. 23956151 Proteomics Clin Appl
Segment and fit thresholding: a new method for image analysis applied to microarray and immunofluorescence data. 26339978 Anal Chem
Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts. 23836919 Mol Cell Proteomics
The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. 28642461 Sci Rep
The detection and discovery of glycan motifs in biological samples using lectins and antibodies: new methods and opportunities. 25727148 Adv Cancer Res
The development of an integrated platform to identify breast cancer glycoproteome changes in human serum. 19782370 J Chromatogr A
The fine specificity of mannose-binding and galactose-binding lectins revealed using outlier motif analysis of glycan array data. 21875884 Glycobiology
The Marker State Space (MSS) method for classifying clinical samples. 23750276 PLoS One
Upregulation of glycans containing 3' fucose in a subset of pancreatic cancers uncovered using fusion-tagged lectins. 25938165 J Proteome Res
Using antibody arrays to measure protein abundance and glycosylation: considerations for optimal performance. 24510592 Curr Protoc Protein Sci
Using lectins in biomarker research: addressing the limitations of sensitivity and availability. 22927350 Proteomics Clin Appl


Pancreatic cancer
Biomarkers for pancreatic cancer
I am interested in characterizing the glycan variants that are associated with cancer and that can be measured as biomarkers.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Photograph of Haab, Brian
Van Andel Research Institute
Person ID
EDRN Title
EDRN Associate Member
To update contact information, please visit the Data Management and Coordinating Center .