37th EDRN Steering Committee Meeting/Breast & Gynecological GYN Collaborative Group Agenda

Tuesday, October 19, 2021

10:00 a.m. to 5:00 p.m. Eastern Daylight Time

Chair: Steven Skates, PhD, Massachusetts General Hospital

Co-Chair: Christopher Li, MD, PhD, Fred Hutchinson Cancer Research Center

NCI Program Director: Christos Patriotis, PhD, National Cancer Institute

 Agenda

10:00 a.m. Welcome
o    Steven Skates, PhD, Massachusetts General Hospital
o    Christos Patriotis, PhD, National Cancer Institute
10:00 a.m. – 2:00 p.m. Team/Collaborative Projects (Supported by Set-asides and Core Funds)
o    What was accomplished and what remains to be done
o    Feasibility of completion
o    Lessons learned
o    Recommendations for improvements
10:00 a.m. – 11:45 a.m. Breast Cancer Projects
10:00 a.m. – 10:35 a.m. 01: Identification of Biomarkers for Non-triple Negative Breast Cancer
o    Christopher Li, MD, PhD, Fred Hutchinson Cancer Research Center (presented by Paul Lampe, PhD, Fred Hutchinson Cancer Research Center)
o    Karen Anderson, MD, PhD, Arizona State University/The Biodesign Institute
10:35 a.m. – 11:10 a.m. 02: Combining Image and Blood Markers in Diagnostic Mammography
o    Jeffrey Marks, PhD, Duke University Medical Center
o    John Heine, PhD, H. Lee Moffitt Cancer Center and Research Institute, Inc.
o    Cha-Mei Tang, PhD, Creatv MicroTech, Inc.
o    Joseph Lo, PhD, Duke University Medical Center
11:10 a.m. 11:45 a.m. 03: Unique Approach Combining Avatar Mice and Targeted Mass Spectrometry to Identify Blood Biomarkers for Early Detection of Breast and Ovarian Cancers
o    Amanda Paulovich, MD, Fred Hutchinson Cancer Research Center
o    Michael Lewis, PhD, Baylor College of Medicine
o    Steven Skates, PhD, Massachusetts General Hospital
11:45 a.m. – 12:15 p.m. Break
12:15 p.m. - 2:00 p.m. Ovarian Cancer Projects
12:15 p.m. - 12:50 p.m. 04: Circulating Autoantibody Biomarkers for Early Detection of Ovarian Cancer
o    Robert Bast, MD, The University of Texas M D Anderson Cancer Center
o    Karen Anderson, MD, PhD, Arizona State University/The Biodesign Institute
o    Charles Drescher, MD, Fred Hutchinson Cancer Research Center
o    Steven Skates, PhD, Massachusetts General Hospital
12:50 p.m. - 1:25 p.m. 05: Uterine Lavage tDNA and Serum Protein Biomarkers in Early Detection of Ovarian Cancer
o    Steven Skates, PhD, Massachusetts General Hospital
o    Charles Drescher, MD, Fred Hutchinson Cancer Research Center
1:25 p.m. 2:00 p.m. 06: Targeted Identification and Collection of STIC with a Falloposcope
o    Ie-Ming Shih, MD, Johns Hopkins Medical Institutions
o    Jennifer Barton, PhD, University of Arizona
2:00 p.m. – 2:30 p.m. Break
2:30 p.m. – 5:00 p.m. Discussion of Potential Clinical Utility Trials
o   Clinical applications
o   Trial design
5:00 p.m. Adjourn for the Day