Final Agenda

Tuesday, June 30, 2020

10:00 a.m. - 6:00 p.m. EDT

Chair:

Pierre Massion, M.D., Vanderbilt-Ingram Cancer Center/Vanderbilt University Medical Center

Co-Chair:

James Herman, M.D., University of Pittsburgh

NCI Program Directors:

Lynn Sorbara, Ph.D., and Karl Krueger, Ph.D., National Cancer Institute

10:00 a.m. - 10:15 a.m. EDT L01: Welcome and Introduction
Objective, Charge and Progress

Pierre Massion, M.D., Vanderbilt University
James Herman, M.D., University of Pittsburgh
Part I: 10:15 a.m. - 3:00 p.m. EDT Site Updates/Progress/Future Study Plans
10:15 a.m. - 10:40 a.m. EDT L02: Optimizing DNA Methylation Detection for Early Lung Cancer
James Herman, M.D., University of Pittsburgh
10:40 a.m. - 10:45 a.m. EDT Q&A
10:45 a.m. - 11:10 a.m. EDT L03: The BU-UCLA Lung Cancer Biomarker Development Laboratory
Marc Lenburg, Ph.D., Boston University
11:10 a.m. - 11:15 a.m. EDT Q&A
11:15 a.m. - 11:40 a.m. EDT L04: 
Steve Dubinett, M.D., University of California, Los Angeles
11:40 a.m. - 11:45 a.m. EDT Q&A
11:45 a.m. - 12:10 p.m. EDT L05: Integration of Biomarker Signatures from Peripheral Blood for Diagnosis, Prognosis, Remission and Recurrence of Lung Cancer
Louise Showe, Ph.D., Wistar Institute
12:10 p.m. - 12:15 p.m. EDT Q&A
12:15 p.m. - 1:00 p.m. EDT Lunch Break
1:00 p.m. - 1:25 p.m. EDT L06: Quantitative Imaging and Radiomics in the Early Detection of Lung Cancer
Matthew Schabath, Ph.D., Moffitt Cancer Center
1:25 p.m. - 1:30 p.m. EDT Q&A
1:30 p.m. - 1:55 p.m. EDT L07:
Harvey Pass, M.D., New York University/Langone Medical Center
1:55 p.m. - 2:00 p.m. EDT Q&A
2:00 p.m. - 2:25 p.m. EDT L08: Non-coding RNAs (ncRNAs) as Biomarkers for Early Detection of Non-Small Cell Lung Cancer in Sputum
Sanford Stass, M.D., University of Maryland
2:25 p.m. - 2:30 p.m. EDT Q&A
2:30 p.m. - 2:55 p.m. EDT L09:
Pierre Massion, M.D., Vanderbilt-Ingram Cancer Center/Vanderbilt University Medical Center
2:55 p.m. - 3:00 p.m. EDT Q&A
3:00 p.m. - 3:15 p.m. EDT Break
Part II: 3:15 p.m. - 5:30 p.m. EDT Discussion should focus on SWOT (Strengths, Weaknesses, Opportunities, and Threats)

What are the strengths of the EDRN and what can we do to further strengthen the Network;
Identify weaknesses and discuss the solutions (mitigation);
Discuss opportunities and highlight prioritized opportunities;
Discuss threats (competing interests/research) and mitigations.

Potential discussion topics in the context of SWOT:

How do we envision the collaboration with industry as a way of the future;
What can we do to focus more attention on including minorities in all biomarker testing and evaluation;
What are the ways that we can tap into and engage with many of the other CBRG and DCP programs, i.e., CIB, MCL, Tumor Atlas;
Discuss increasing the capacity for accrual for future studies;
How can we expand the role of the BRLs?
Discuss the potential of another collaborative group that is focused on common assays/technologies/biomarker validation?
Can the EDRN consider the integration of small clinical trials to move clinical utility forward?
How can we best bring junior investigators in our collaborative group;
How do we increase the number of collaborations between our lung collaborative group members?
Is EDRN ready to apply Universal Cancer Approach - multianalyte for Pan Cancer Detection?
5:30 p.m. - 6:00 p.m. EDT Summary Write up
Drs. Pierre Massion, James Herman, Lynn Sorbara, and Karl Krueger will summarize the information for presentation at the general meeting tomorrow.
6:00 p.m. EDT Adjourn