8 Gene Panel for Barretts Esophagus

Aliases
  • 8 Gene Panel for Barretts Esophagus
  • 8-gene Panel for Barrett's Esophagus
  • Meltzer 8-marker panel for Esophageal Adenocarcinoma
Description
Eight methylation biomarkers - p16, RUNX3, HPP1 (HGNC name TMEFF2), NELL1, TAC1, SST, AKAP12 and CDH13 - were tested in a restrospective multicenter double-blinded validation study for their accuracy in predicting neoplastic progression in Barretts Esophagus. Hypermethylation of p16, RUNX3 and HPP1 has been show to occur in early Barretts Esophagus-related neoplastic progression and predicts progression risk. Several of the panel (NELL1, TAC1, SST, AKAP12 and CDH13) were also shown to be methylated early and often in Barretts Esophagus-related neoplastic progression.
Attributes
QA State
Accepted
Type
Genomic
HGNC Name
Certifications
QA State for Esophagus
Under Review

 Non-Public Biomarker

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