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Specimen Reference Sets

Documentation, EDRN guidelines, and application forms for specimen reference sets

General Documents for Reference Sets

EDRN Guidelines

Application Form for EDRN Reference Sets (Fillable Word Document)

Ovarian & Breast Cancer Reference Sets

Biomarker Reference Sets for Cancers in Women (BRSCW) (PDF)
Description of pooled reference sets for ovarian and breast cancer serum specimens
BRSCW Application Form (Fillable Word Document)

Breast Cancer Reference Set

Breast Reference Set Summary (PDF)

Breast Reference Set Protocol (PDF)

Breast Reference Set Participant and Clinical Forms (PDF)

Breast Reference Set Application Form (Fillable Word Document)

Lung Cancer Reference Sets

Lung Cancer Reference Set Documentation (PDF)
The goal of the NCI/EDRN/SPORE Lung Cancer Biomarkers Group (LCBG) is to develop the requisite sample resources to pre-validate serum/plasma biomarkers for the early diagnosis of lung cancer.
Lung Cancer Reference Set Application Form (Online Form)

Colon Cancer Reference Set

Colon Cancer Reference Set Description (PDF)


Prostate Cancer Reference Set

Prostate Cancer Reference Set Description (PDF)
One of the goals of the EDRN Genitourinary (GU) Collaborative Group is the establishment of a biologic sample set on men prior to prostate biopsy, in association with clinical information and common data elements appropriate for evaluation of risk and prognosis of prostate cancer.

Liver (Hepatocellular Carcinoma) Reference Set

Hepatocellular Carcinoma Reference Set Description (PDF)
2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh ( no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.