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Miscellaneous Resources

Various other resources.

Contents

Knowledge Object 510(k) SUBSTANTIAL EQUIVALENCE DETERMINATION DECISION SUMMARY
Knowledge Object [1] Clinicopathic features of biopsies
Knowledge Object [1] Pre-PLCO dataset, all records unblinded.
Knowledge Object [1] Receiver-operator characteristic curve analysis for the eight methylation biomarkers in 50 progressors and 145 non-progressors
Knowledge Object [2] Normalized methylation values of HPP1, p16 and RUNX3
Knowledge Object [3] Logistic regression and overfitting correction for the 2 year, 4 year and combined models
Knowledge Object [4] Receiver-operator characteristic (ROC) curves for the uncorrected 8-marker and 8-marker-plus-age panels, overfitting-corrected ROC curves for the 8-marker and 8-marker-plus-age panels, and ROC cur
Knowledge Object [5] Incremental AUC values contributed by an eight-marker-plus-age biomarker panel to that of age alone
Knowledge Object [6] Specificity and sensitivity for 2 year, 4 year and combined models
Knowledge Object [7] Overfitting-corrected predictiveness curve analyses in 2 year, 4 year and combined models
Knowledge Object [8] Risk stratification of BE patients by predictiveness curves of 8-marker panel, age alone, and 8-marker-plus-age panel in combined, 2-year and 4-year prediction models.
Knowledge Object CARET study website, for more information on patient population.
Knowledge Object CARET website, for additional information on the study population.
Knowledge Object Draft Directional Insert
Knowledge Object Entrez Gene entry for human mesothelin, MSLN. Entrez Gene lists SMRP as a synonym for MSLN. SMRP is an alternative form of MSLN.
Knowledge Object Entrez Protein Reference Sequence for 72 kDa type IV collagenase isoform a preproprotein [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for annexin I [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for apolipoprotein A-I preproprotein [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for chitinase-3-like protein 1 precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for eotaxin precursor [Homo sapiens] CCL11
Knowledge Object Entrez Protein Reference Sequence for epidermal growth factor receptor isoform a precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for human insulin-like growth factor-binding protein 2 precursor IGFBP2
Knowledge Object Entrez Protein Reference Sequence for human SLPI secretory leukocyte peptidase inhibitor
Knowledge Object Entrez Protein Reference Sequence for IGF2 [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for IL6R (interleukin 6 receptor)
Knowledge Object Entrez Protein Reference Sequence for insulin-like growth factor-binding protein 1 precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for keratin, type I cytoskeletal 19 [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for leptin precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for macrophage migration inhibitory factor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for mesothelin isoform 1 preproprotein [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for MMP7 matrix metallopeptidase 7
Knowledge Object Entrez Protein Reference Sequence for osteopontin isoform e [Homo sapiens] SPP1
Knowledge Object Entrez Protein Reference Sequence for prolactin precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for serotransferrin precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for spondin-2 precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for stromelysin-1 preproprotein [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for transthyretin precursor [Homo sapiens]
Knowledge Object Entrez Protein Reference Sequence for vascular cell adhesion protein 1 isoform a precursor [Homo sapiens]
Knowledge Object FDA approval of ROMA
Knowledge Object FDA Medical Device description of Hybritech p2PSA assay
Knowledge Object FDA news release for OVA1 approval
Knowledge Object FDA product classification
Knowledge Object FDA web page describing approval of AFP-L3
Knowledge Object FDA website for PCA3 assay
Knowledge Object GenBank entry for human BAC clone RP11-499F19
Knowledge Object GenBank nucleotide sequence for human PMS2L15
Knowledge Object GenBank translated protein sequence for human PMS2L15
Knowledge Object Gene entry for human TP63
Knowledge Object Gene entry for human VEGFA
Knowledge Object GeneCards entry for ANGPTL3
Knowledge Object GeneCards entry for human AATK, also known as Lmr1
Knowledge Object GeneCards entry for human ACKR3
Knowledge Object GeneCards entry for human ACTR3
Knowledge Object GeneCards entry for human ADAM12
Knowledge Object GeneCards entry for human ADH5
Knowledge Object GeneCards entry for human AFP, of which AFP-L3 is an isoform
Knowledge Object GeneCards entry for human AIM1
Knowledge Object GeneCards entry for human AKR1B10
Knowledge Object GeneCards entry for human ALDH3A1
Knowledge Object GeneCards entry for human ALG10
Knowledge Object GeneCards entry for human AMACR
Knowledge Object Genecards entry for human ANG
Knowledge Object GeneCards entry for human ANO1
Knowledge Object GeneCards entry for human ANXA2
Knowledge Object GeneCards entry for human AP3B2
Knowledge Object GeneCards entry for human APAF1
Knowledge Object GeneCards entry for human APC
Knowledge Object GeneCards entry for human APEX1
Knowledge Object GeneCards entry for human ARHGEF16
Knowledge Object GeneCards entry for human ATF3
Knowledge Object GeneCards entry for human ATP6AP1
Knowledge Object GeneCards entry for human ATP6V1G1
Knowledge Object GeneCards entry for human BANK1
Knowledge Object GeneCards entry for human BAT4 (GPANK1)
Knowledge Object GeneCards entry for human BMP1
Knowledge Object GeneCards entry for human BMX
Knowledge Object GeneCards entry for human BPIFA1
Knowledge Object GeneCards entry for human BRCA1
Knowledge Object GeneCards entry for human BVES
Knowledge Object GeneCards entry for human C1S
Knowledge Object GeneCards entry for human C9
Knowledge Object GeneCards entry for human C15orf48
Knowledge Object GeneCards entry for human CAGE1
Knowledge Object GeneCards entry for human CALCA
Knowledge Object GeneCards entry for human CAPN1
Knowledge Object GeneCards entry for human CAPNS1
Knowledge Object GeneCards entry for human CAT
Knowledge Object GeneCards entry for human CBLC
Knowledge Object GeneCards entry for human CCDC102B
Knowledge Object GeneCards entry for human CCL2
Knowledge Object GeneCards entry for human CCL5 (RANTES)
Knowledge Object GeneCards entry for human CCL15
Knowledge Object GeneCards entry for human CCL18, also known as MIP-4
Knowledge Object GeneCards entry for human CCL27
Knowledge Object GeneCards entry for human CCND1
Knowledge Object GeneCards entry for human CD1A
Knowledge Object GeneCards entry for human CD30 ligand, TNFSF8
Knowledge Object GeneCards entry for human CDCP1
Knowledge Object GeneCards entry for human CDH1
Knowledge Object GeneCards entry for human CDK5
2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.