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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Establishment of a serum standard for use in high-throughput proteomic Semmes, John
Expression based markers for breast cancer detection Marks, Jeffrey
GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett's Esophagus Progression to Dysplasia and Adenocarcinoma    Recognizing that novel potential biomarkers are continually being identified and will need to be validated in a rapid, efficient, and scientifically ... Brenner, Dean
Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer The Early Detection Research Network of the NCI is charged with the discovery, development and validation of biomarkers for early detection and prognosis ... Zhang, Hui L.
HNPCC colon cancer-associated SELDI mass spectrometry protein profiles in serum Lynch, Henry
Hepatocellular carcinoma Early Detection Strategy study Marrero, Jorge
Hereditary Cancer Institute family study specimen bank Lynch, Henry
High-Throughput Evaluation of Breast Cancer Markers The objective of this study is to use a combination of AMT proteomics and ELISA microarray testing to discover and validate novel biomarkers for breast cancer. Zangar, Richard (Rick) C.
Hollingsworth - Aggressive vs Indolent 2012 Hollingsworth, Michael
Hollingsworth - Aggressive vs Indolent 2012 Study Overview. We will examine DNA extracted from FFPE sections from approximately 200 different surgically resected primary pancreatic tumors from the UNMC ... Hollingsworth, Michael
Identification of New Markers in Normal and Abnormal Pap Smears Unger, Elizabeth R.
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. BACKGROUND: Lung cancer is the leading cause of cancer death in men and women in the United States and Western Europe. Over 160,000 Americans die of this ... Anglim, Paul
Identification of biomarkers for lung cancer in never smokers The overall goal of this project is to identify, verify and apply biomarkers for the early diagnosis or risk assessment of lung cancer in never smokers. The ... Gazdar, Adi
Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Gene expression profile analysis of lung cancers revealed the transactivation of an immunoglobulin-like molecule Nectin-4 in the majority of non-small cell ... Takano, Atsushi
Identification of protein and genetic biomarkers of prostate cancer and risk factors for progression of disease Thompson, Ian M.
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis The detection of nonsmall cell lung cancer (NSCLC) at an early stage presents a daunting challenge due to the lack of a specific noninvasive marker. The ... Chen, Xi
In-depth proteomic analysis of non-small cell lung cancer to discover molecular targets and candidate biomarkers Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in ... Carbone, David P
Inflammation as a Potential Marker of Risk ad Progression for Prostate Cancer Thompson, Ian M.
Integrated Development of Novel Molecular Markers Sidransky, David
LIver Reference Set Applicant (Rapid) Beretta-FHCRC (2011) Beretta, Laura
LIver Reference Set Applicant (Rapid) Qu-Quest (2011) Qu, Kevin
LIver Reference Set Applicant (Rapid) Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia Lynch, Henry
Liver Cancer Specimen Reference Set Application (Rapid): Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Reference Set (Rapid) Norman (2012) Feng, Ziding
Liver Reference Set Applicant (Full): Lubman - Univ of Michigan (2011) Lubman, David
Liver Reference Set Applicant (Full): Yamada - Wako (2011) Yamada, Hiro
Liver Reference Set Applicant (Rapid #1): Lubman - Univ of Michigan We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Reference Set Applicant (Rapid #2) Beretta-FHCRC (2011) Beretta, Laura
Liver Reference Set Applicant (Rapid #2): Lubman - Univ of Michigan We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David