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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Breast Reference Set Application: Richard Zangar-PNNL (2012) Our immediate goal is to define a set of biomarkers (composed of circulating plasma proteins) that can be used to distinguish between true and false screens, ... Zangar, Richard (Rick) C.
Breast tissue array Chia, David
CLUE Studies: Evaluating Biomarkers of Carcinogenesis Helzlsouer, Kathy
Canary TMA This protocol describes a multi-center, retrospective, case-cohort tissue microarray (TMA) study to evaluate tissue biomarkers for their ability to predict ... Nelson, Peter S
Chemokine Prostate Cancer Biomarkers STUDY DESIGN 1. The need for pre-validation studies. Preliminary data from our laboratory demonstrates a potential utility for CXCL5 and CXCL12 as biomarkers ... Macoska, Jill
Clinical Utility of Urinary CD90 as a Biomarker for Prostate Cancer Detection Tumor-associated stromal cells differ from normal gland-associated stromal cells in gene expression. Genes up-regulated in these stromal cells are potential ... Liu, Alvin Y.
Clinical Validation of Molecular Signatures of Cervical Neoplasia Unger, Elizabeth R.
Clinical and Analytical Validation of Cancer Biomarkers: Developmental Studies Chan, Daniel
Clinical validation of an autoantibody test for lung cancer BACKGROUND: Autoantibodies may be present in a variety of underlying cancers several years before tumours can be detected and testing for their presence may ... Boyle, Peter
Collaborative study on SELDI biomarker discovery and serum protein profiling of lung cancers Semmes, John
Colon Reference Set Application: Robert Getzenberg - Johns Hopkins (2008) The goal of this project is to confirm the early validation of CCSA-3 and CCSA-4 as biomarkers for the early detection of adenocarcinoma of the colon and ... Getzenberg, Robert H.
Colon Reference Set Application: Mary Disis - University of Washington (2008) The proposed study aims to validate the diagnostic value of a panel of serum antibodies for the early detection of colorectal cancer (CRC). We have developed a ... Disis, Mary L
Colon Reference Set Application: Moncef Jendoubi - Milagen (2006) Confidential Jendoubi, Moncef
Colon Reference Set Application: Nam Kim - DiaDexus (2008) The EDRN Colorectal reference samples will be useful in confirming the potential application of novel serum markers for colorectal cancer that can detect ... Kim, Nam
DCIS Team Project Both overtreatment and undertreatment of DCIS are pervasive problems given that no useful approaches for identifying which DCIS patients are likely or highly ... Li, Christopher
DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients. We used MethyLight assays to analyze DNA methylation status of 27 genes on 49 paired cancerous and noncancerous tissue samples from non-small cell lung cancer ... Feng, Qinghua
Depo-Provera and Breast Cancer: Epidemiology/Pathology The injectable contraceptive depot medroxy-progesterone acetate (DMPA) (Depo-Provera) is commonly used by women worldwide, and it contains the same progestin ... Li, Christopher
Detecting Breast Cancer Signatures in Body Fluids Trock, Bruce
Detecting breast cancer protein signatures in body fluid Semmes, John
Detection of Bladder CA by Microsatellite Analysis (MSA) Goal 1: To determine sensitivity and specificity of microsatellite analysis (MSA) of urine sediment, using a panel of 15 microsatellite markers, in detecting ... Schoenberg, Mark P.
Detection of Serum Markers of Breast Cancer by SELDI Marks, Jeffrey
Detection of Serum Proteomic Patterns and SNPs in Breast Cancer: A Pilot Study Esserman, Laura J.
Detection of cancer DNA markers in urine Block, Timothy
Development and Clinical Validation of Biomarkers for Prostate Cancer Partin, Alan W
Development and Evaluation of a Tumor Marker for Prostate Cancer Major strides in the early detection, staging, monitoring, and risk stratification of men with prostate cancer have been realized over the last few decades. ... Partin, Alan W
Development of FISH-based assay for early detection of high grade cervical dysplasia Unger, Elizabeth R.
Development of a magneto-nanosensor (MNS) array for prostate cancer biomarkers Our goal is to develop a blood-based biomarker magneto-nanosensor array for the accurate early detection and prognostication of prostate cancer Gambhir, Sanjiv
Development of a multiplexed tumor-associated autoantibody-based blood test for the detection of non-small cell lung cancer. PURPOSE: Non-small cell lung cancer (NSCLC) has an overall 5-year survival of <15%; however, the 5-year survival for stage I disease is over 50%. ... Farlow, Erin C.
Development of paraffin-based expression profiles to predict minimal vs. substantial risk of disease progression using retrospective datasets Esserman, Laura J.
Dubinett - Targeted Sequencing 2012 we propose to use targeted massively parallel DNA sequencing to identify somatic alterations within mutational hotspots in matched sets of primary lung tumors, ... Dubinett, Steve
2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement