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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
PTM Microarray: Request for Year 3 Set-Aside Funds We hypothesize that PTMs on proteins that are secreted by the breast will provide a more sensitive method for detecting breast cancer than analysis of the ... Zangar, Richard (Rick) C.
Pancreatic Cancer Early Detection Stem Cell Biomarkers (CA117452 Set-Aside) Lokshin, Anna
Pancreatic Cancer Reference Set Applicant: Honda (2014) Honda, Kazufumi
Pancreatic Cancer Reference Set Applicant: NCI Honda (2014) Honda, Kazufumi
Pancreatic Cystic Fluid Reference Set The proposed reference set will be designed to evaluate biomarkers for the following applications aimed at determining whether a patient would benefit from ... Brand, Randall E.
Pancreatic Ref Set Applicant: Batra 2014 Batra, Surinder
Pancreatic Ref Set Applicant: Hollingsworth 2014 Hollingsworth, Michael
Pancreatic Reference Set Applicant-Haab (2012) This study will address the clinical problems of early detection and diagnosis. The samples were obtained from patients with early-stage pancreatic cancer, ... Haab, Brian
Pancreatic Reference Set Applicant-Killary (2012) Killary, Ann M.
Pancreatic Reference Set Applicant: Blasutig 2014 Blasutig, Ivan
Pancreatic Reference Set Application- Ann Killary-MD Anderson (2012) ELISA assays. We propose to screen a two gene panel (TNC/TFPI) from functional genomic pathways approaches, by ELISA assays, in a collection of blinded plasma ... Killary, Ann M.
Pancreatic Reference Set Application: Brian Haab-Van Andel (2012) New markers are greatly needed for the detection and diagnosis of pancreatic cancer. Patients at high risk for developing pancreatic cancer (for, example ... Haab, Brian
Pancreatic Reference Set Application: Ivan Blasutig-University of Toronto (2014) Blasutig, Ivan
Pancreatic Reference Set Application: Kazufumi Honda-National Cancer Center (2014) Honda, Kazufumi
Pancreatic Reference Set Application: Michael Hollingsworth-University of Nebraska (2014) Hollingsworth, Michael
Pancreatic Reference Set Application: Surinder Batra- University of Nebraska (2014) Batra, Surinder
Panel of serum biomarkers for the diagnosis of lung cancer PURPOSE: Currently, a blood test for lung cancer does not exist. Serum biomarkers that could aid clinicians in making case management decisions would be ... Patz Jr., Edward F.
Pattern of antioxidant and DNA repair gene expression in normal airway epithelium associated with lung cancer diagnosis. In previous studies, we reported that key antioxidant and DNA repair genes are regulated differently in normal bronchial epithelial cells of lung cancer cases ... Blomquist, Thomas
Pentraxin-3 is a novel biomarker of lung carcinoma PURPOSE: Our objective was to validate the performance of three new candidate lung cancer biomarkers, pentraxin-3 (PTX3), human kallikrein 11 (KLK11), and ... Diamandis, Eleftherios P.
Phase II Validation of a New Panel of Biomarkers for Early Detection of Ovarian Cancer While all cancer patients could potentially benefit from earlier detection and prevention, the development of new screening technologies and chemoprevention ... Mor, Gil
Polyp Prediction Study Meltzer, Stephen
Pre-Validation of Metabolomic Biomarkers of Prostate Cancer Chinnaiyan, Arul M.
Preliminary Clinical Characterization of Serum Biomarkers for Colorectal Neoplasms Brenner, Dean
Preliminary Validation of Biomarkers for the Detection of Colorectal Adenomas (Team Project #1) 1   AIMS We propose a GI Collaborative biomarker validation project with the goal of identifying those biomarkers developed by the GI collaborative that will ... Brenner, Dean
Presence of simian virus 40 DNA sequences in human Lymphoma specimens were collected and analyzed for the presence of SV40 sequences. The DMCC analyzed data for Adi Gazdar Gazdar, Adi
Profiling tumor-associated antibodies for early detection of non-small cell lung cancer. BACKGROUND: A blood test for non-small cell lung cancer (NSCLC) may be a valuable tool for use in a comprehensive lung cancer screening strategy. Here we ... Zhong, Li
Prognostic Markers in Lynch Syndrome Colorectal Cancers Lynch, Henry
Prostate Active Surveillance Study Primary Objective: To discover and confirm biomarkers that predict aggressive disease as defined by pre-specified histological, PSA, clinical criteria, or ... Lin UW, Daniel W.
Prostate Rapid Pre-Validation Set Determine which markers move to validation using the prospectie prostate reference set samples. Sanda, Martin
Prostate Rapid Reference Set Applicant: Diamandis - Mt Sinai (2006) Diamandis, Eleftherios P.
2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.