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EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.


Title Abstract Investigator
Molecular Progression of Methylation in Bladder Cancer Sidransky, David
Mutational load distribution analysis (MLDA) in pancreatic cancer Certain p16 mutation carriers showed mutation elevations in the specific Ki-ras and p53 alleles significantly higher than normal, similar to controls with ... Lynch, Henry
NYU Lung Cancer Biomarker Center A. SPECIFIC AIMS 1. To develop and prospectively follow a large cohort at high-risk for lung cancer. Individuals are recruited to one of two different ... Rom, William
National Ovarian Cancer Early Detection Program Blood and Genetics Fishman, David
New Biomarkers & Dysplastic Respiratory Epithelium Franklin, Wilbur Alan
Novel Surveillance Strategies For Hereditary Nonpolyposis Colon Cancer Family Members Lynch, Henry
Ornithine decarboxylase (ODC) Polymorphism and Breast and Prostate Cancer Helzlsouer, Kathy
Ovarian Cancer Screening Pilot Trial In High Risk Women BACKGROUND: No proven ovarian cancer (OC) screening strategy exists for women who are at increased risk for the disease. A risk of ovarian cancer algorithm ... Lynch, Henry
PCA3 Validation Study and Urinary Reference Set Prostate cancer (PCa) is the third leading cause of cancer-related deaths among United States men, accounting for 33% of such diagnosed cancers.(1) An ... Wei, John
PLCO Ovarian Phase III Validation Study The obvious appeal of a strategy for the early detection of ovarian cancer is based upon the tendency for the disease to present at advanced stages associated ... Cramer, Daniel
PTM Microarray: Request for Year 3 Set-Aside Funds We hypothesize that PTMs on proteins that are secreted by the breast will provide a more sensitive method for detecting breast cancer than analysis of the ... Zangar, Richard (Rick) C.
Pancreatic Cancer Early Detection Stem Cell Biomarkers (CA117452 Set-Aside) Lokshin, Anna
Pancreatic Cancer Reference Set Applicant: Honda (2014) Honda, Kazufumi
Pancreatic Cystic Fluid Reference Set Brand, Randall E.
Pancreatic Ref Set Applicant: Batra 2014 Batra, Surinder
Pancreatic Ref Set Applicant: Hollingsworth 2014 Hollingsworth, Michael
Pancreatic Reference Set Applicant-Haab (2012) This study will address the clinical problems of early detection and diagnosis. The samples were obtained from patients with early-stage pancreatic cancer, ... Haab, Brian
Pancreatic Reference Set Applicant-Killary (2012) Killary, Ann M.
Pancreatic Reference Set Applicant: Blasutig 2014 Blasutig, Ivan
Panel of serum biomarkers for the diagnosis of lung cancer PURPOSE: Currently, a blood test for lung cancer does not exist. Serum biomarkers that could aid clinicians in making case management decisions would be ... Patz Jr., Edward F.
Pattern of antioxidant and DNA repair gene expression in normal airway epithelium associated with lung cancer diagnosis. In previous studies, we reported that key antioxidant and DNA repair genes are regulated differently in normal bronchial epithelial cells of lung cancer cases ... Blomquist, Thomas
Pentraxin-3 is a novel biomarker of lung carcinoma PURPOSE: Our objective was to validate the performance of three new candidate lung cancer biomarkers, pentraxin-3 (PTX3), human kallikrein 11 (KLK11), and ... Diamandis, Eleftherios P.
Phase II Validation of a New Panel of Biomarkers for Early Detection of Ovarian Cancer While all cancer patients could potentially benefit from earlier detection and prevention, the development of new screening technologies and chemoprevention ... Mor, Gil
Polyp Prediction Study Meltzer, Stephen
Pre-Validation of Metabolomic Biomarkers of Prostate Cancer Chinnaiyan, Arul M.
Preliminary Clinical Characterization of Serum Biomarkers for Colorectal Neoplasms Brenner, Dean
Preliminary Validation of Biomarkers for the Detection of Colorectal Adenomas (Team Project #1) 1   AIMS We propose a GI Collaborative biomarker validation project with the goal of identifying those biomarkers developed by the GI collaborative that will ... Brenner, Dean
Presence of simian virus 40 DNA sequences in human Lymphoma specimens were collected and analyzed for the presence of SV40 sequences. The DMCC analyzed data for Adi Gazdar Gazdar, Adi
Profiling tumor-associated antibodies for early detection of non-small cell lung cancer. BACKGROUND: A blood test for non-small cell lung cancer (NSCLC) may be a valuable tool for use in a comprehensive lung cancer screening strategy. Here we ... Zhong, Li
Prognostic Markers in Lynch Syndrome Colorectal Cancers Lynch, Henry
Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.