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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Lung Reference Set A (Full) Applicant: Takacs - Biosystems (2010) Not listed
Lung Reference Set A Application: Edward Hirschowitz - University of Kentucky (2009) We are continuing validation with two advanced objectives: 1) To evaluate assay performance for established lung cancer diagnosed in a clinical population 2) ... Hirschowitz, Edward
Lung Reference Set A Application: Dawn Coverley- University of York (2011) A variant of the nuclear matrix factor Ciz1 is prevalent in lung cancer cell lines and tumours, but not in adjacent lung tissue, giving rise to a protein that ... Coverley, Dawn
Lung Reference Set A Application: LaszloTakacs - Biosystems (2010) We would like to access the NCI lung cancer Combined Pre-Validation Reference Set A in order to further validate a lung cancer diagnostic test candidate. Our ... Not listed
Lung Reference Set A Application: Lee Goodglick/ Eleftherios Diamandis- UCLA/MSH (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
Lung Reference Set C Application: Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Early detection may help improve survival from lung cancer. In this study, our goal was to derive and validate a signature from the proteomic analysis of ... Rahman, Jamshedur S.M.
MALDI Dilution Data: Randolph Feng, Ziding
MMR protein expression in HNPCC Lynch, Henry
MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014) Rosser, Charles J
MSA Ref Set Applicant: Rosser Rosser, Charles J
Methylation & Proteomics-Based Detection of Bladder Cancer Study never Launched Cairns, Paul
Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers. BACKGROUND: The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and ... Richards, Kristy L.
Methylation tumor markers in HNPCC Lynch, Henry
Molecular Basis of Barrett's -Associated Carcinogenesis Stass, Sanford
Molecular Genetics of Urinary Bladder Carcinoma Czerniak, Bogdan
Molecular Progression of Methylation in Bladder Cancer Sidransky, David
Mutational load distribution analysis (MLDA) in pancreatic cancer Certain p16 mutation carriers showed mutation elevations in the specific Ki-ras and p53 alleles significantly higher than normal, similar to controls with ... Lynch, Henry
NYU Lung Cancer Biomarker Center A. SPECIFIC AIMS 1. To develop and prospectively follow a large cohort at high-risk for lung cancer. Individuals are recruited to one of two different ... Rom, William
National Ovarian Cancer Early Detection Program Blood and Genetics Fishman, David
New Biomarkers & Dysplastic Respiratory Epithelium Franklin, Wilbur Alan
Novel Surveillance Strategies For Hereditary Nonpolyposis Colon Cancer Family Members Lynch, Henry
Ornithine decarboxylase (ODC) Polymorphism and Breast and Prostate Cancer Helzlsouer, Kathy
Ovarian Cancer Screening Pilot Trial In High Risk Women BACKGROUND: No proven ovarian cancer (OC) screening strategy exists for women who are at increased risk for the disease. A risk of ovarian cancer algorithm ... Lynch, Henry
PASS Applicant: Etzioni Etzioni, Ruth
PASS Reference Set Application: Ruth Etzioni-William Beaumont Hospital (2014) Etzioni, Ruth
PASS Reference Set Application: TMPRSS2-ERG-PCA-PASS-Dan Lin-UW (2010) see Publication Lin UW, Daniel W.
PASS-OPKO Collaboration Lin UW, Daniel W.
PCA3 Reference Set Application: T2-Erg-Martin Sanda-Emory (2014) We hypothesize that combining T2:erg (T2:erg) fusion and PCA3 detection in urine collected after digital rectal exam can improve the specificity of identifying ... Sanda, Martin
PCA3 Validation Study and Urinary Reference Set see Publication Wei, John
2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement