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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Hollingsworth - Aggressive vs Indolent 2012 (359) Hollingsworth, Michael
Identification of New Markers in Normal and Abnormal Pap Smears Unger, Elizabeth R.
Identification of biomarkers for lung cancer in never smokers The overall goal of this project is to identify, verify and apply biomarkers for the early diagnosis or risk assessment of lung cancer in never smokers. The ... Gazdar, Adi
Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Gene expression profile analysis of lung cancers revealed the transactivation of an immunoglobulin-like molecule Nectin-4 in the majority of non-small cell ... Takano, Atsushi
Identification of protein and genetic biomarkers of prostate cancer and risk factors for progression of disease Thompson, Ian M.
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis The detection of nonsmall cell lung cancer (NSCLC) at an early stage presents a daunting challenge due to the lack of a specific noninvasive marker. The ... Chen, Xi
In-depth proteomic analysis of non-small cell lung cancer to discover molecular targets and candidate biomarkers Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in ... Carbone, David P
Inflammation as a Potential Marker of Risk ad Progression for Prostate Cancer Thompson, Ian M.
Integrated Development of Novel Molecular Markers Sidransky, David
LIver Reference Set Applicant (Rapid) Beretta-FHCRC (2011) Beretta, Laura
LIver Reference Set Applicant (Rapid) Qu-Quest (2011) Qu, Kevin
LIver Reference Set Applicant (Rapid) Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia Lynch, Henry
Liver Cancer Specimen Reference Set Application (Rapid): Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Full Reference Set Application :Timothy Block - Drexel Univ (2010) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Liver Full Reference Set Application: David Lubman - Univ of Michigan (2011) In this work we will perform the next step in the biomarker development and validation. This step will be the Phase 2 validation of glycoproteins that have ... Lubman, David
Liver Full Reference Set Application: Hiro Yamada - Wako (2011) Wako has received new 510(k) clearance for Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) and Des-gamma-carboxy prothrombin (DCP) ... Yamada, Hiro
Liver Rapid Reference Set Application ( #2): Lubman - Univ of Michigan (2010) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Rapid Reference Set Application (#1): David Lubman - Univ of Michigan (2009) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Rapid Reference Set Application (#1): Laura Beretta-FHCRC (2011) Test 2 candidate biomarkers for early detection of HCC. Marker S and Marker L. Beretta, Laura
Liver Rapid Reference Set Application (#2): Laura Beretta-FHCRC (2011) Test 2 candidate biomarkers for early detection of HCC. Marker S and Marker L. Beretta, Laura
Liver Rapid Reference Set Application: Gary Norman-INOVA (2012) We have developed a new and novel assay for the detection of Golgi protein 73 (GP73), also known as Golgi membrane protein 1 (Golm1) or Golgi phosphoprotein 2 ... Norman, Gary L.
Liver Rapid Reference Set Application: Gianluigi Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Rapid Reference Set Application: Hiro Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Liver Rapid Reference Set Application: Kevin Qu-Quest (2011) We propose to evaluate the performance of a novel serum biomarker panel for early detection of hepatocellular carcinoma (HCC). This panel is based on markers ... Qu, Kevin
Liver Rapid Reference Set Application: Timothy Block - Drexel Univ (2008) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Liver Reference Set Applicant (Rapid #2) Beretta-FHCRC (2011) Beretta, Laura
Lung A Reference Set (Full) Applicant: Coverley-York (2011) Coverley, Dawn
Lung C Reference Set (Full): Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
Lung Cancer Specimen Reference Set A (Full) Application: Goodglick/Diamandis (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement