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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis The detection of nonsmall cell lung cancer (NSCLC) at an early stage presents a daunting challenge due to the lack of a specific noninvasive marker. The ... Chen, Xi
In-depth proteomic analysis of non-small cell lung cancer to discover molecular targets and candidate biomarkers Advances in proteomic analysis of human samples are driving critical aspects of biomarker discovery and the identification of molecular pathways involved in ... Carbone, David P
Inflammation as a Potential Marker of Risk ad Progression for Prostate Cancer Thompson, Ian M.
Integrated Development of Novel Molecular Markers Sidransky, David
LIver Reference Set Applicant (Rapid) Beretta-FHCRC (2011) Beretta, Laura
LIver Reference Set Applicant (Rapid) Qu-Quest (2011) Qu, Kevin
LIver Reference Set Applicant (Rapid) Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia Lynch, Henry
Liver Cancer Specimen Reference Set Application (Rapid): Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Reference Set (Rapid) Norman (2012) Feng, Ziding
Liver Reference Set Applicant (Full): Lubman - Univ of Michigan (2011) Lubman, David
Liver Reference Set Applicant (Full): Yamada - Wako (2011) Yamada, Hiro
Liver Reference Set Applicant (Rapid #1): Lubman - Univ of Michigan (2009) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Reference Set Applicant (Rapid #2) Beretta-FHCRC (2011) Beretta, Laura
Liver Reference Set Applicant (Rapid #2): Lubman - Univ of Michigan (2010) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Reference Set Application (Full): Block - Drexel Univ (2010) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Liver Reference Set Application (Rapid): Block - Drexel Univ (2008) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Lung A Reference Set (Full) Applicant: Coverley-York (2011) Coverley, Dawn
Lung C Reference Set (Full): Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
Lung Cancer Specimen Reference Set A (Full) Application: Goodglick/Diamandis (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
Lung Cancer Specimen Reference Set A (Full) Application: Hirschowitz - University of Kentucky (2009) We are continuing validation with two advanced objectives: 1) To evaluate assay performance for established lung cancer diagnosed in a clinical population 2) ... Hirschowitz, Edward
Lung Reference Set A (Full) Applicant: Takacs - Biosystems (2010) Not listed
Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Early detection may help improve survival from lung cancer. In this study, our goal was to derive and validate a signature from the proteomic analysis of ... Rahman, Jamshedur S.M.
MALDI Dilution Data: Randolph Feng, Ziding
MMR protein expression in HNPCC Lynch, Henry
Methylation & Proteomics-Based Detection of Bladder Cancer To determine sensitivity and specificity of quantitative real-time methylation specific PCR (qMSP) of urine sediment DNA, using a panel of several methylated ... Cairns, Paul
Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers. BACKGROUND: The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and ... Richards, Kristy L.
Methylation tumor markers in HNPCC Lynch, Henry
Molecular Basis of Barrett's -Associated Carcinogenesis Stass, Sanford
Molecular Genetics of Urinary Bladder Carcinoma Czerniak, Bogdan
Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.