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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Liver Reference Set Application (Full): Block - Drexel Univ (2010) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Liver Reference Set Application (Rapid): Block - Drexel Univ (2008) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Lung A Reference Set (Full) Applicant: Coverley-York (2011) Coverley, Dawn
Lung C Reference Set (Full): Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
Lung Cancer Specimen Reference Set A (Full) Application: Goodglick/Diamandis (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
Lung Cancer Specimen Reference Set A (Full) Application: Hirschowitz - University of Kentucky (2009) We are continuing validation with two advanced objectives: 1) To evaluate assay performance for established lung cancer diagnosed in a clinical population 2) ... Hirschowitz, Edward
Lung Reference Set A (Full) Applicant: Takacs - Biosystems (2010) Not listed
Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Early detection may help improve survival from lung cancer. In this study, our goal was to derive and validate a signature from the proteomic analysis of ... Rahman, Jamshedur S.M.
MALDI Dilution Data: Randolph Feng, Ziding
MMR protein expression in HNPCC Lynch, Henry
Methylation & Proteomics-Based Detection of Bladder Cancer To determine sensitivity and specificity of quantitative real-time methylation specific PCR (qMSP) of urine sediment DNA, using a panel of several methylated ... Cairns, Paul
Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers. BACKGROUND: The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and ... Richards, Kristy L.
Methylation tumor markers in HNPCC Lynch, Henry
Molecular Basis of Barrett's -Associated Carcinogenesis Stass, Sanford
Molecular Genetics of Urinary Bladder Carcinoma Czerniak, Bogdan
Molecular Progression of Methylation in Bladder Cancer Sidransky, David
Mutational load distribution analysis (MLDA) in pancreatic cancer Certain p16 mutation carriers showed mutation elevations in the specific Ki-ras and p53 alleles significantly higher than normal, similar to controls with ... Lynch, Henry
NYU Lung Cancer Biomarker Center A. SPECIFIC AIMS 1. To develop and prospectively follow a large cohort at high-risk for lung cancer. Individuals are recruited to one of two different ... Rom, William
National Ovarian Cancer Early Detection Program Blood and Genetics Fishman, David
New Biomarkers & Dysplastic Respiratory Epithelium Franklin, Wilbur Alan
Novel Surveillance Strategies For Hereditary Nonpolyposis Colon Cancer Family Members Lynch, Henry
Ornithine decarboxylase (ODC) Polymorphism and Breast and Prostate Cancer Helzlsouer, Kathy
Ovarian Cancer Screening Pilot Trial In High Risk Women BACKGROUND: No proven ovarian cancer (OC) screening strategy exists for women who are at increased risk for the disease. A risk of ovarian cancer algorithm ... Lynch, Henry
PCA3 Validation Study and Urinary Reference Set Independent of serum PSA level, PCA3 score will refine the risk of having cancer detected on an extended template prostate biopsy. Wei, John
PLCO Ovarian Phase III Validation Study The obvious appeal of a strategy for the early detection of ovarian cancer is based upon the tendency for the disease to present at advanced stages associated ... Cramer, Daniel
PTM Microarray: Request for Year 3 Set-Aside Funds We hypothesize that PTMs on proteins that are secreted by the breast will provide a more sensitive method for detecting breast cancer than analysis of the ... Zangar, Richard (Rick) C.
Pancreatic Cancer Early Detection Stem Cell Biomarkers (CA117452 Set-Aside) Lokshin, Anna
Pancreatic Cystic Fluid Reference Set Brand, Randall E.
Pancreatic Reference Set Applicant-Haab (2012) Haab, Brian
Pancreatic Reference Set Applicant-Killary (2012) Killary, Ann M.