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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
Integrated Development of Novel Molecular Markers Sidransky, David
LIver Reference Set Applicant (Rapid) Beretta-FHCRC (2011) Beretta, Laura
LIver Reference Set Applicant (Rapid) Qu-Quest (2011) Qu, Kevin
LIver Reference Set Applicant (Rapid) Yamada - Wako (2011) Measure clinical effectiveness of AFP-L3 and DCP for early detection of HCC in patient samples collected prospectively during surveillance. However since such ... Yamada, Hiro
Light Scattering Spectroscopy for the Detection of Colorectal Neoplasia Lynch, Henry
Liver Cancer Specimen Reference Set Application (Rapid): Giannelli - Univ of Bari (2008) To evaluate biomarker performance in an out-side cohort of LC and HCC patients Giannelli, Gianluigi
Liver Reference Set (Rapid) Norman (2012) Pepe, Margaret Sullivan
Liver Reference Set Applicant (Full): Lubman - Univ of Michigan (2011) Lubman, David
Liver Reference Set Applicant (Full): Yamada - Wako (2011) Yamada, Hiro
Liver Reference Set Applicant (Rapid #1): Lubman - Univ of Michigan (2009) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Reference Set Applicant (Rapid #2) Beretta-FHCRC (2011) Beretta, Laura
Liver Reference Set Applicant (Rapid #2): Lubman - Univ of Michigan (2010) We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC ... Lubman, David
Liver Reference Set Application (Full): Block - Drexel Univ (2010) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Liver Reference Set Application (Rapid): Block - Drexel Univ (2008) The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular ... Block, Timothy
Lung A Reference Set (Full) Applicant: Coverley-York (2011) Coverley, Dawn
Lung C Reference Set (Full): Rachel Ostroff - SomaLogics (2010) Analysis of the EDRN lung biomarker samples will enable the next step in development of a clinical diagnostic assay for the differential diagnosis of lung ... Ostroff, Rachel
Lung Cancer Specimen Reference Set A (Full) Application: Goodglick/Diamandis (2009) To study of the utility of KLK8, 11, 12, 13, and 14 profiles in diagnosing lung cancer. Chia, David
Lung Cancer Specimen Reference Set A (Full) Application: Hirschowitz - University of Kentucky (2009) We are continuing validation with two advanced objectives: 1) To evaluate assay performance for established lung cancer diagnosed in a clinical population 2) ... Hirschowitz, Edward
Lung Reference Set A (Full) Applicant: Takacs - Biosystems (2010) Not listed
Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Early detection may help improve survival from lung cancer. In this study, our goal was to derive and validate a signature from the proteomic analysis of ... Rahman, Jamshedur S.M.
MALDI Dilution Data: Randolph Pepe, Margaret Sullivan
MMR protein expression in HNPCC Lynch, Henry
Methylation & Proteomics-Based Detection of Bladder Cancer To determine sensitivity and specificity of quantitative real-time methylation specific PCR (qMSP) of urine sediment DNA, using a panel of several methylated ... Cairns, Paul
Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers. BACKGROUND: The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and ... Richards, Kristy L.
Methylation tumor markers in HNPCC Lynch, Henry
Molecular Basis of Barrett's -Associated Carcinogenesis Stass, Sanford
Molecular Genetics of Urinary Bladder Carcinoma Czerniak, Bogdan
Molecular Progression of Methylation in Bladder Cancer Sidransky, David
Mutational load distribution analysis (MLDA) in pancreatic cancer Certain p16 mutation carriers showed mutation elevations in the specific Ki-ras and p53 alleles significantly higher than normal, similar to controls with ... Lynch, Henry
NYU Lung Cancer Biomarker Center A. SPECIFIC AIMS 1. To develop and prospectively follow a large cohort at high-risk for lung cancer. Individuals are recruited to one of two different ... Rom, William
News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html