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Protocols

EDRN investigators protocols. The following is a list of the EDRN protocols that have been captured and curated. Additional information will be added as it is available. Contact information is provided as part of the detail for each protocol.

Contents

Title Abstract Investigator
A Methylation Panel for Bladder Cancer Gazdar, Adi
Affinity-based strategies to fast track development of colon cancer biomarkers Our goal is to discover plasma and tissue-based tumor biomarkers that work well enough together to identity colon cancer at early stages, lead to accurate ... Lampe, Paul
Antibodies Against Tumor Antigens or Mucin Epitopes in Ovarian Cancer Cramer, Daniel
Assessment of Clinical Potential of Digital SNP Analysis Helzlsouer, Kathy
Aurora Kinase A as a Biomarker for the Detection of Bladder Cancer - Supplemental Pre-Validation Protocol Czerniak, Bogdan
Autoantibody Approach for Serum-Based Detection of Head and Neck Cancer Our long term goal is to improve survival of patients with head and neck squamous cell carcinoma (HNSCC) through early detection using simple noninvasive serum ... Tainsky, Michael A.
BBD Reference Set Application: Jeffery Marks-Duke (2015) Marks, Jeffrey
BRSCW Ref Set Application: Anna Lokshin - Univ of Pitts (2008) Validate biomarkers identified using Luminex bead-based arrays in case/control sets (individual samples) in reference sets Lokshin, Anna
BRSCW Reference Set Application: Anu Mathew - Meso Scale (2006) 46 markers were tested on pooled case samples and on control samples. Mathew, Anu
BRSCW Reference Set Application: Eleftherios Diamandis - Mt Sinai (2006) Examine kallikreins as ovarian cancer biomarkers Diamandis, Eleftherios P.
BRSCW Reference Set Application: GeorgeTuszynski - Temple University (2012) The marker GASP-1 was evaluated in the pooled breast cancer reference set. It did not seem to be elevated relative to controls. Tuszynski, George
BRSCW Reference Set Application: James Morre - NOX Technologies Inc. (2009) Evaluation using NOX Technologies ECTO-NOX blot diagnostic 2-D gel electrophoretic cancer detection system in combination with a sandwich ELISA of our ... Morre, D. James
BRSCW Reference Set Application: Joe Buechler - Biosite Inc (2009) Over 40 marker assays are available to run on the samples. These include markers such as Osteopontin, Mesothelin, Periostin, Endoglin, intestinal Fatty Acid ... Buechler, Joe
BRSCW Reference Set Application: Karen Abbott -University of Arkansas (2014) Our earlier glycoproteomic studies have identified bisecting glycoslyation and core fucosylation changes on particular glycoproteins in endometrioid ovarian ... Abbott, Karen
BRSCW Reference Set Application: Michael Birrer-Massachusetts General Hospital (2013) Validate FGF18 and GPR172A in reference set Birrer, Michael
BRSCWRef Set Application: Michael Wilson - EIC Laboratories, Inc (2007) The selected markers are well established as "standard" markers fo ra range of cancers, and have been analyzed in the reference set as a benchmark for ... Wilson, Michael S.
Barrett's Esophagus Methylation Profiles We propose a nested case-control study of biomarkers in the setting of BE. By bringing together research institutions with large populations of patients with ... Meltzer, Stephen
Benign Breast Disease Team Project To identify women diagnosed with atypical ductal hyperplasia (ADH) who are at increased risk of developing invasive breast cancer (IBC) and who might benefit ... Engstrom, Paul
Biomarker Detection Using NAPPA Tumor Antigen Arrays Cancer patients spontaneously generate autoantibodies (AAb) to tumor-derived proteins. To detect AAb, we have probed novel high-density custom protein ... LaBaer, Joshua
Biomarker Detection Using NAPPA Tumor Antigen Arrays: EDRN Supplement The overall goal of this project application for the EDRN set-aside funds is to focus our collaborative efforts to identify p53 mutation-specific antibody ... Anderson, Karen
Biomarker Dev Lab At Moffitt Supplement Tockman, Melvyn S.
Biomarker Development Laboratory Zhao, Yingming
Biomarker Discovery for Renal Cell Carcinoma Through Serum, Urine and Tissue Protein Profiles Basler, Joseph W.
Biomarker Reference Sets for Cancers in Women The purpose of this study is to develop a standard reference set of specimens for use by investigators participating in the National Cancer Institutes Early ... Cramer, Daniel
Biomarkers for Prostate and Bladder Cancer CD26+ cancer cells and CD90+ tumor-associated stromal cells were sorted from tumor tissue. Dataset analysis with transcriptomes of CD26+ luminal, CD104+ basal, ... Liu, Alvin Y.
Biomarkers for early detection of pancreatic cancer Background: The clinical management of pancreatic cancer is severely hampered by the absence of effective screening tools. Methods: Sixty-seven biomarkers ... Lokshin, Anna
Biomarkers for the Early Detection of Pancreatic Cancer Killary, Ann M.
Biomarkers in Familial Multiple Myeloma Lynch, Henry
Biomarkers of Risk for Colorectal Neoplasia (Team Project #2) The goal of this project is to evaluate biomarkers in normal colonic mucosa to determine their relationship to the occurrence of short- and long-term ... Schoen, Robert E.
Biomarkers to Distinguish Aggressive Cancers from Non-aggressive or Non- progressing cancers We hypothesize that our novel Biomarker Panel of Auto-antibodies can distinguish aggressive, symptom diagnosed lung cancer from non-aggressive, screen-detected ... Rom, William
2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement