Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Protocols / Seattle Area Hormone and Reproductive Epidemiology Breast Cancer Study
Not an EDRN Protocol

Seattle Area Hormone and Reproductive Epidemiology Breast Cancer Study

1035

No involved investigator sites defined.

The SHARE Study (Seattle Area Hormone And Reproductive Epidemiology Breast Cancer Study) is a five-year, population-based case-control study, funded by the National Institutes of Health, to investigate the relationship between hormone replacement therapy (HRT) and invasive lobular and invasive ductal breast cancer among women 55 to 74-years of age. The case group of 1043 women consists of 271 invasive lobular, 330 invasive ductal and lobular, and 442 invasive ductal, breast cancer cases. The control group consists of 469 controls drawn from the general population. The specific study hypotheses that were tested: 1. Is the use of combined estrogen-progestin hormone replacement therapy (CHRT) associated with an increase in the incidence of invasive lobular breast cancer in women aged 55-74a 2. Is the use of CHRT associated with an increase in the incidence of invasive ductal breast cancer in women aged 55-74a 3. Does the duration, patterns and/or recency of CHRT use influence the size of the associationa 4. Is the use of CHRT associated with particular tumor marker profiles or characteristics of lobular and ductal breast cancers

There are currently no biomarkers annotated for this protocol.

No datasets are currently associated with this protocol.


2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement