Targeted Sequencing for Discovery and Validation of DNA Methylation Markers of Colon Cancer Metastasis
No coordinating investigator defined.
No involved investigator sites defined.
Colon cancer is the second leading cause of cancer death in the United States. A key issue in treating colon cancer patients is inability to accurately predict tumors that have metastatic potential and require adjuvant chemotherapy. This project will test the model that tumor metastases arise from intra-tumor heterogeneity generated by DNA methylation events, and that detecting these events can provide a predictve signature of tumors with poor outcome
There are currently no biomarkers annotated for this protocol.
No datasets are currently associated with this protocol.