PTM Microarray: Request for Year 3 Set-Aside Funds
We hypothesize that PTMs on proteins that are secreted by the breast will provide a more sensitive method for detecting breast cancer than analysis of the parent protein. We will antibody microarrays to have examine 9 circulating proteins, each of which is known to be actively secreted by the breast, for several structurally and functionally distinct PTMs. We will determine if these modified proteins have the potential to used in the early detection of breast cancer.
There are currently no biomarkers annotated for this protocol.
No datasets are currently associated with this protocol.