Prostate and Urologic Cancers Research Group
- Developed Prostate Cancer Risk Calculator (http://www.prostate-cancer-risk-calculator.com)
- Discovered sarcosine as a metabolite biomarker in tissue and urine
- Constructed standard reference sets for rapid triage and validation of biomarkers for prostate cancer
- Developed molecular assay and FISH for detection of T2S:ERG fusion in urine and tissue, respectively
- Completed validation of PCA3 as a urine-based test for early detection and diagnosis of prostate cancer
- Completed validation of %[-2]proPSA to improve PSA-based detection of prostate cancer; IVD pending FDA review
- Completed MSA validation study for early detection of bladder cancer
- Discovery of cancer specific gene fusions (TMPRSS2-ETV1; TMPRSS2:ERG)
