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Zhong TAA signature



QA State: Curated
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The TAA signature is a diagnostic array of five markers capable of distinguishing patients with non-small cell lung cancer (NSCLC) from normal control subjects. The diagnostic array was developed by enriching and screening phage-expressed tumor-associated proteins, and using these in a fluorescent protein microarray to identify and measure multiple non-small cell lung cancer-associated antibodies and show how simultaneous measurements can be combined into a single diagnostic assay. Although the identity of the phage-expressed proteins is not critical for use in a diagnostic assay, the sequences were compared with the GenBank database to obtain possible identity. The five proteins in the final diagnostic array are GAGE7, BAC clone RP11-499F19, SEC15L2, PMS2P7 (PMS2L15), and EEF1A.

Panel Details


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Curated


The data indicates that antibody profiling is a promising approach that could achieve high diagnostic accuracy for non-small cell lung cancer.


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2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.