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Zhong 5-antibody panel for Lung Cancer



QA State: Curated
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A potential autoantibody profile was developed to screen for non-small cell lung cancer. 212 immunogenic phage-expressed proteins were statistically ranked for their individual reactivity with 23 stage I cancer patient and 23 risk-matched control samples. Measurements of the five most predictive antibody markers in 46 cases and controls were combined. While the identity of these phage-expressed proteins is not critical for use in a diagnostic assay, the identities were determined through a nucleotide search of GenBank. Markers are: paxillin, SEC 15L2, BAC clone RP11-499F19, XRCC5, and MALAT1.

Panel Details


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Curated


Antibody profiling may be a useful tool for early detection of NSCLC.


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2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place January 20–21, 2016 in Bethesda, Maryland.

Announcement 08/26/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Wednesday-Thursday, January 20-21, 2016, on the NCI campus. More information will be available later this summer.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.