Aliases:This biomarker is also known as:
- V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1,
- Proto-Oncogene C-Yes,
- Proto-Oncogene Tyrosine-Protein Kinase YES,
- Tyrosine-Protein Kinase Yes,
- Cellular Yes-1 Protein,
- Yamaguchi Sarcoma Oncogene,
YES1, also known as YES, is a non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. It is the cellular homolog of the Yamaguchi sarcoma virus oncogene and belongs to the src family of proteins. YES1 is involved in many phosphorylation reactions, including a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
|QA State:||Under Review|
There are no datasets associated with this biomarker.