Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / VTA1

VTA1

Basics

Aliases:
This biomarker is also known as:
  • chromosome 6 open reading frame 55,
  • Q9NP79,
  • HSPC228,
  • vacuolar protein sorting-associated protein VTA1 homolog,
  • SKD1-binding protein 1,
  • Vps20-associated 1 homolog (S. cerevisiae),
  • LYST-interacting protein 5,
  • DRG-1,
  • C6orf55,
  • dopamine-responsive gene 1 protein,
  • SBP1,
  • homolog of mouse SKD1-binding protein 1,
  • LIP5,
  • Dopamine-responsive gene 1 protein,
  • DRG1,
  • My012,
  • C6ORF55,

View in BioMuta

Description…

VTA1 (C6ORF55) is involved in activities of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes. VTA1 is thought to be a cofactor of VPS4A/B. VTA1 is involved in HIV-1 budding. It has been shown by similarity to be involved in the sorting and down-regulation of EGFR.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

VTA1 (C6ORF55) was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. VTA1 (C6ORF55) was not in the group of 13 selected for further validation.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html