Aliases:This biomarker is also known as:
- Thyrotropin beta chain,
- INN=Thyrotropin alfa,
- Thyrotropin alfa,
- thyrotropin beta subunit,
- Thyroid-stimulating hormone subunit beta,
- thyroid stimulating hormone, beta,
- thyrotropin subunit beta,
TSH, a secreted protein belonging to the glycoprotein hormones subunit beta family, is essential for the control of thyroid structure and metabolism. The four human glycoprotein hormones - chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH)- are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Congenital hypothyroidism is caused by mutation in the TSH gene.
|QA State:||Under Review|
There are no datasets associated with this biomarker.