Aliases:This biomarker is also known as:
- CD30 antigen ligand,
- tumor necrosis factor ligand superfamily member 8,
- tumor necrosis factor (ligand) superfamily, member 8,
- CD153 antigen,
- CD30 ligand,
TNFSF8, also known as CD30 ligand, is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. TNFSF8 binds to TNFRSF8/CD30, a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. TNFSF8 has been shown to induce proliferation of T-cells. It also enhances cell proliferation of some lymphoma cell lines, and induces cell death and reduces cell proliferation of other lymphoma cell lines. There are two different isoforms encoded by two transcript variants.
|QA State:||Under Review|
There are no datasets associated with this biomarker.