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STOML2

Basics

Aliases:
This biomarker is also known as:
  • HSPC108,
  • stomatin-like 2,
  • stomatin (EPB72)-like 2,
  • SLP-2,
  • stomatin-like protein 2,
  • EPB72-like protein 2,
  • SLP2,

View in BioMuta

Description…

STOML2, also known as SLP-2 or stomatin-like 2, is a mitochondrial protein that is thought to regulate the biogenesis and the activity of mitochondria, and through this regulation play a role in cell activities such as cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

STOML2, also known as SLP-2 or stomatin-like 2, is overexpressed in many cancers, including breast cancer. STOML2 (SLP-2) expression and ERBB2 (HER-2/neu) protein expression are associated with decreased breast cancer patient survival.

Performance Comment

STOML2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html