Aliases:This biomarker is also known as:
- spondin 2, extracellular matrix protein,
- spondin 2,
- Differentially expressed in cancerous and non-cancerous lung cells 1,
Spondin-2 is a cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. It binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Spondin-2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the extacellular matrix for microbial pathogens. Spondin-2 also binds bacterial lipopolysaccharide.
|QA State:||Under Review|
There are no datasets associated with this biomarker.