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SERPINA1

Basics

Aliases:
This biomarker is also known as:
  • PRO2275,
  • alpha-1-antitrypsin null,
  • alpha1AT,
  • serine (or cysteine) proteinase inhibitor, clade A, member 1,
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • A1A,
  • AAT,
  • Alpha-1-antiproteinase,
  • MGC23330,
  • hAAT,
  • protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin,
  • Serpin A1,
  • alpha-1-antitrypsin,
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • PI,
  • Alpha-1 protease inhibitor,
  • MGC9222,
  • A1AT,
  • PI1,

View in BioMuta

Description…

Alpha-1-antitrypsin is secreted and is an extracellular serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Elevation of alpha1-AT serum levels have been observed in the course of a large number of malignant diseases. Several transcript variants encoding the same protein have been found for this gene.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.

Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html