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RAB13

Basics

Aliases:
This biomarker is also known as:
  • RAS-associated protein RAB13,
  • Cell growth-inhibiting gene 4 protein,
  • growth-inhibiting gene 4 protein,
  • cell growth-inhibiting gene 4 protein,
  • RAB13, member RAS oncogene family,
  • ras-related protein Rab-13,

View in BioMuta

Description…

RAB13 is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). RAB13 is thought to participate in polarized transport, in the assembly and/or the activity of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. There are several alternatively spliced transcript variants for this gene, and a pseudogene located on chromosome 12.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

RAB13 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement