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This biomarker is also known as:
  • LCA,
  • protein tyrosine phosphatase, receptor type, c polypeptide,
  • T200 leukocyte common antigen,
  • GP180,
  • T200,
  • LY5,
  • Leukocyte common antigen,
  • EC,
  • CD45 antigen,
  • T200 glycoprotein,
  • L-CA,
  • CD45R,
  • CD45,
  • B220,
  • protein tyrosine phosphatase, receptor type, C,
  • receptor-type tyrosine-protein phosphatase C,

View in BioMuta


PTPRC is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. PTPRC is required for T-cell activation through the antigen receptor. PTPRC contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and is classified as a receptor type PTP.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

PTPRC was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.