PRMT1
Basics
Aliases:
This biomarker is also known as:- HMT2,
- Interferon receptor 1-bound protein 4,
- IR1B4,
- HCP1,
- ANM1,
- Histone-arginine N-methyltransferase PRMT1,
- Protein arginine N-methyltransferase 1,
- HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2,
- HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae),
- HRMT1L2,
Description…
PRMT1 is an arginine N-methyltransferase that functions as a histone methyltransferase specific for H4. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. PRMT1 may also be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.PRMT1 is widely expressed.
Attributes
| QA State: | Under Review |
|---|---|
| Type: | Protein |
| Short Name: |
Datasets
There are no datasets associated with this biomarker.
Organs
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Studies
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Publications
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Resources
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.





