Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / PQBP1

PQBP1

Basics

Aliases:
This biomarker is also known as:
  • Sutherland-Haan X-linked mental retardation syndrome,
  • MRXS8,
  • Polyglutamine tract-binding protein 1,
  • NPW38,
  • Npw38,
  • polyglutamine-binding protein 1,
  • SHS,
  • nuclear protein containing WW domain 38 kD,
  • RENS1,
  • polyglutamine tract-binding protein 1,
  • mental retardation, X-linked 55,
  • MRX55,
  • 38 kDa nuclear protein containing a WW domain,
  • polyglutamine binding protein 1,
  • PQBP-1,
  • MRXS3,

View in BioMuta

Description…

polyglutamine binding protein 1

Attributes

QA State: Curated
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Prostate

Attributes

Phase: One
QA State: Curated

Overview

No additional prostate data available.

Performance Comment

Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC, ALDH1A2, TRIM22, RBPMS, HSPB8.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.

Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html