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PCCA

Basics

Aliases:
This biomarker is also known as:
  • PCCase alpha subunit,
  • propionyl-CoA carboxylase alpha chain, mitochondrial,
  • propanoyl-CoA:carbon dioxide ligase alpha subunit,
  • PCCase subunit alpha,
  • EC 6.4.1.3,
  • propionyl CoA carboxylase, alpha polypeptide,
  • propionyl Coenzyme A carboxylase, alpha polypeptide,
  • pccA complementation group,
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha,

View in BioMuta

Description…

PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PCCA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement