Aliases:This biomarker is also known as:
- NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa,
- NADH-ubiquinone oxidoreductase 42 kDa subunit,
- complex I 42kDa subunit,
- NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD),
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial,
- Complex I-42kD,
NDUFA10 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional breast data available.
NDUFA10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.