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MYO5A

Basics

Aliases:
This biomarker is also known as:
  • myosin V,
  • myoxin,
  • myosin-12,
  • myosin VA (heavy polypeptide 12, myoxin),
  • myosin-Va,
  • MYR12,
  • Myosin-12,
  • Myoxin,
  • GS1,
  • dilute myosin heavy chain, non-muscle,
  • unconventional myosin-Va,
  • MYO5,
  • MYH12,
  • Myosin heavy chain 12,
  • myosin VA (heavy chain 12, myoxin),
  • myosin, heavy polypeptide kinase,
  • Dilute myosin heavy chain, non-muscle,

View in BioMuta

Description…

The MYO5A gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. The MYO5A protein functions as a processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. MYO5A is also involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. Different isoforms, encoded by alternatively spliced transcript variants, have been reported.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

MYO5A was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement