Aliases:This biomarker is also known as:
- Glycosylation-inhibiting factor,
- phenylpyruvate tautomerase,
- macrophage migration inhibitory factor (glycosylation-inhibiting factor),
- macrophage migration inhibitory factor,
- L-dopachrome tautomerase,
- L-dopachrome isomerase,
MIF, a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation, plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. MIF is also closely related to tumorigenesis.
|QA State:||Under Review|
There are no datasets associated with this biomarker.