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Massion 4-marker FISH panel for lung cancer



QA State: Curated
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The combination of these 4 probes, TP63, MYC, CEP3, and CEP6, offered a sensitivity of 82% for lung cancer and a specificity of 58%. These results indicate that specific cytogenetic alterations present in preinvasive lung lesions are closely associated with the diagnosis of lung cancer and may therefore have value in assessing lung cancer risk.

Panel Details


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The following organs have data associated with this biomarker…



Phase: Two
QA State: Curated


In this study, we found that the high frequency of non-coding centromeric alterations (CEP3 and CEP 6) was independently associated with a diagnosis of lung cancer (Table 2), and therefore although not specifically linked to tumorigenesis, it is probably part of the genomic instability coming along with the disease process.


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2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.