Massion 4-marker FISH panel for lung cancer
The combination of these 4 probes, TP63, MYC, CEP3, and CEP6, offered a sensitivity of 82% for lung cancer and a specificity of 58%. These results indicate that specific cytogenetic alterations present in preinvasive lung lesions are closely associated with the diagnosis of lung cancer and may therefore have value in assessing lung cancer risk.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
In this study, we found that the high frequency of non-coding centromeric alterations (CEP3 and CEP 6) was independently associated with a diagnosis of lung cancer (Table 2), and therefore although not specifically linked to tumorigenesis, it is probably part of the genomic instability coming along with the disease process.
No associated resources found.