Aliases:This biomarker is also known as:
- latent transforming growth factor beta binding protein 2,
- chromosome 14 open reading frame 141,
- Latent-transforming growth factor beta-binding protein 2,
LTBP2, the largest member of the latent transforming growth factor (TGF)-beta binding protein family, possesses unique regions and is most similar to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. LTBP2 forms part of the large latent transforming growth factor beta precursor complex; removal is essential for activation of complex. It is expressed in lung, weakly expressed in heart, placenta, liver and skeletal muscle.
|QA State:||Under Review|
There are no datasets associated with this biomarker.