Aliases:This biomarker is also known as:
- luteinizing hormone beta polypeptide,
- Luteinizing hormone subunit beta,
- luteinizing hormone beta subunit,
- Lutropin beta chain,
- lutropin subunit beta,
- interstitial cell stimulating hormone, beta chain,
The pituitary glycoprotein hormone family includes follicle stimulating hormone (FSH), luteinizing hormone (LH), chorionic gonadotropin (CG), and thyroid-stimulating hormone (TSH). All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. LHB, the beta subunit of luteinizing hormone, confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
|QA State:||Under Review|
There are no datasets associated with this biomarker.