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KRAS

Basics

Aliases:
This biomarker is also known as:
  • transforming protein p21,
  • C-K-RAS,
  • NS,
  • c-K-ras2 protein,
  • KRAS2,
  • K-RAS4A,
  • PR310 c-K-ras oncogene,
  • K-RAS4B,
  • KRAS1,
  • K-ras p21 protein,
  • RASK2,
  • KI-RAS,
  • c-Kirsten-ras protein,
  • NS3,
  • K-RAS2A,
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,
  • K-RAS2B,
  • oncogene KRAS2,
  • cellular c-Ki-ras2 proto-oncogene,
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,

View in BioMuta

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement